Evidence map›Paper›PMID 35018046›Full record

ArticleJournal of pharmacy & bioallied sciences2021

Comparative Evaluation of Salivary Biomarker Levels in e-Cigarette Smokers and Conventional Smokers.

Abhishek Verma, Kumar Anand, Manish Bhargava, Amulya Kolluri, Madhuresh Kumar, Devendra H Palve

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of pharmacy & bioallied sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 3 pooled it
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 3 syntheses or guidelines pooled it, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Abhishek VermaDepartment of Periodontology and Implantology, Buddha Institute of Dental Science and Hospital, Patna, bihar, India.
Kumar AnandDepartment of Oral Medicine and Radiology, Buddha Institute of Dental Sciences and Hospital, Patna, bihar, India.
Manish BhargavaDepartment of Oral Pathology and Microbiology, Manav Rachna Dental College, Faridabad, Haryana, India.
Amulya KolluriDepartment of Periodontology and Implantalogy, Meghna Institute of Dental Sciences, Nizamabad, Telangana, India.
Madhuresh KumarDepartment of Oral Pathology and Microbiology, Buddha Institute of Dental Science and Hospital, Patna, India.
Devendra H PalveDepartment of Oral Pathology and Microbiology, Swargiya Dadasaheb Kalmegh Smruti Dental College and Hospital, Nagpur, Maharashtra. India.
Gautam Buddha University · INKamineni Institute of Dental Sciences · INManav Rachna International Institute of Research and Studies · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe cigarette smoking and its effect on the inflammatory cytokine levels in the smoker's saliva depicted the influence of electronic cigarettes on oral cytokine levels in oral fluids are scarce in the literature.

objectivesThe present trial was conducted to compare and determine the proinflammatory and anti-inflammatory cytokines in whole stimulated saliva samples of electronic cigarette smokers, conventional smokers, and participants with no smoke exposure. MATERIALS AND

methodsSixty adult participants were divided into the following four groups of nonsmokers, current smokers, smokers smoking both conventional and e-cigarettes, and e-cigarette smokers. The saliva samples were assessed for Interleukins (IL-1B, 6, 8, 10, and IL-1RA), C-reactive protein (CRP), and tumor necrosis factor-alpha (TNF-α) using enzyme-linked immunosorbent assay. Plaque scores and Gingival Index, and body mass index were also calculated.

resultsStatistically significant (

conclusionWithin its limitations, the present study concludes that smoking e-cigarettes whether solely or in combination with conventional smoking increases the levels of proinflammatory cytokines such as TNF-α and IL-1 β with decreased counter IL-1RA levels.

Indexed as

E-cigarettegingival indexinflammatory mediatorsplaque scoressalivary biomarkerssmoking

Identifiers

PMID35018046
PMCPMC8686896
OpenAlexW3212205047

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.