Evidence map›Paper›PMID 35017975›Full record

ArticleJournal of pharmacy & bioallied sciences2021

Determination of Role of Type 16 Human Papillomavirus and Risk Factors in Assessing Oropharyngeal Cancer Survival.

Meenakshi Bhasin, Harkanwal Preet Singh, Padam Singh, Rachna Dhingra, Saniya Arora Kohli, Anurag Azad

Open access · goldAbstract read
In one paragraph

Article in Journal of pharmacy & bioallied sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 76% of its field
1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors at 5 institutions in 1 country.

Meenakshi BhasinReader, Department of Oral Medicine Radiology, Hitkarini Dental College and Hospital, Jabalpur, Madhya Pradesh, India.
Harkanwal Preet SinghDepartment of Oral Pathology and Microbiology, Dasmesh Institute of Research and Dental Sciences, Faridkot, Punjab, India.
Padam SinghDepartment of Periodontics, Desh bhagat Dental College, Mandigobindghar, Punjab, India.
Rachna DhingraAssistant professor, Department of ENT, GGS Medical college and Hospital, Faridkot, Punjab, India.
Saniya Arora KohliDepartment of Oral Medicine Radiology, Hitkarni Dental College and Hospital, Jabalpur, Madhya Pradesh, India.
Anurag AzadDepartment of Oral Surgery, Bhabha College of Dental Sciences, Bhopal, Madhya Pradesh, India.
Baba Farid University of Health Sciences · INBhabha Hospital · INDesh Bhagat University · INGuru Gobind Singh Medical College and Hospital · INRajasthan Dental College and Hospital · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIt is ascertained that the survival rate of patients infected with type 16 human papillomavirus (HPV16) positive is better as compared to those infected with HPV16 negative. The present study was conducted to determine rgw role of HPV16 and risk factors in assessing oropharyngeal cancer (OPC) death. METHODOLOGY: A total of 102 clinically and histologically proven cases of oral pharyngeal cancer were included. Seropositivity for HPV16 E6 as a marker of HPV16-positive cancer was estimated.

resultsOut of 102 patients, there were 70 males and 32 females. Significant risk factors associated with OPC survival overall in the univariate analysis was female sex (hazard ratio [HR] 0.54, 95% confidence level [CL]: 0.36-80), alcohol use >2 drinks/day (HR 1.54, 95% CL: 1.12-2.08), smoking >10 pack-years (HR 2.20, 95% CL: 1.42-3.58), moderate dental (HR 1.54, 95% CL: 1.02-2.32), underweight (HR 2.24, 95% CL: 1.34-3.60), and Stage IV cancer (HR 2.82, 95% CL: 1.76-4.40). There was significant low risk for death among HPV16 positive (HR 0.48, 95% CL: 0.32-0.70).

conclusionHPV16 status is an independent prognostic factor for OPC deaths. The common risk factors were female gender, moderate oral care, underweight body mass index, excessive alcohol, and smoking tobacco.

Indexed as

Oropharyngeal cancersmoking tobaccotype 16 human papillomavirus

Identifiers

PMID35017975
PMCPMC8686906
OpenAlexW3212509922

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LicenceCC BY-NC-SA
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.