ArticleBulletin of the World Health Organization2022
Prevention of mother-to-child transmission of hepatitis B virus in antenatal care and maternity services, Mozambique.
Article in Bulletin of the World Health Organization, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 4 of them syntheses that pooled it.
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Who cites it
20 citing papers in PubMed, 4 syntheses or guidelines pooled it, 20 citations in OpenAlex.
- Vertical transmission of hepatitis B virus in the WHO African region: a systematic review and meta-analysis.The Lancet. Global health · 2025Pooled it
- Epidemiology of hepatitis B virus infection among pregnant women in Africa: a systematic review and meta-analysis.BMC infectious diseases · 2024Pooled it
- Towards contextualized complex systems approaches to scaling-up hepatitis B birth-dose vaccination in the African region: a qualitative systematic review.Frontiers in public health · 2024Pooled it
- Pooled it
- The Level of Knowledge, Attitude, Practice, and Adherence of Obstetricians and Gynecologists Towards the Triple Elimination Program (HIV, Syphilis, Hepatitis B) in Maternal Services at Government and Private Hospitals in Jakarta.International journal of environmental research and public health · 2026Article
- Integrated Service Delivery Models for Triple Elimination of Mother to Child Transmission of Human Immunodeficiency Virus, Syphilis, and Hepatitis B Virus: A Global Systematic Review and Meta-Analysis.Healthcare (Basel, Switzerland) · 2026Review
- Local insights into hepatitis B Virus: genotype distribution and clinical profiles among HIV/HBV co-infected patients in Maputo, Mozambique.BMC infectious diseases · 2026Article
- Strengthening the hepatitis B care cascade to prevent vertical transmission in Africa: a call to empower midwives.BMJ global health · 2026Article
- Article
- Developing strategies for integrating Hepatitis B Virus infection testing and treatment into routine PMTCT services in Ghana's Upper West Region: a rapid qualitative study applying the CFIR-ERIC matching tool.BMC public health · 2025Article
- Serological and Molecular Characterization of the Hepatitis B Virus in Blood Donors in Maputo City, Mozambique.Viruses · 2025Article
- Epidemiological and clinical profile of hepatitis B infection in ART-naïve people living with HIV in Maputo, Mozambique: a cross-sectional study.BMJ public health · 2025Article
- Global elimination of HBV: Is it really achievable?Journal of viral hepatitis · 2024Review
- Knowledge, attitudes, practices and prevalence of hepatitis B and C and hepatitis B vaccination coverage among public sector healthcare workers in Cambodia.Global health & medicine · 2024Article
- Antenatal hepatitis B virus sero-prevalence, risk factors, pregnancy outcomes and vertical transmission rate within 24 months after birth in a high HIV prevalence setting.BMC infectious diseases · 2023Article
- Enhancing interventions for prevention of mother-to-child- transmission of hepatitis B virus.JHEP reports : innovation in hepatology · 2023Review
- Hepatitis B virus genotypes and drug resistance mutations circulating in blood donors in Beira, Mozambique.PloS one · 2023Article
- Rapid Diagnostic Test for Hepatitis B Virus Viral Load Based on Recombinase Polymerase Amplification Combined with a Lateral Flow Read-Out.Diagnostics (Basel, Switzerland) · 2022Article
- Prevalence of hepatitis B virus and immunity status among healthcare workers in Beira City, Mozambique.PloS one · 2022Article
- Article
Corrections and comments
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Authors and funding
10 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo pilot an intervention on the prevention of mother-to-child transmission (PMTCT) of hepatitis B virus (HBV) in an antenatal care and maternity unit in Maputo, Mozambique, during 2017-2019.
methodsWe included HBV in the existing screening programme (for human immunodeficiency virus (HIV) and syphilis) for pregnant women at their first consultation, and followed mother-child dyads until 9 months after delivery. We referred women who tested positive for hepatitis B surface antigen (HBsAg) for further tests, including hepatitis B e antigen (HBeAg) and HBV viral load. According to the results, we proposed tenofovir for their own health or for PMTCT. We administered birth-dose HBV vaccine and assessed infant HBV status at 9 months.
findingsOf 6775 screened women, 270 (4.0%) were HBsAg positive; in those for whom data were available, 24/265 (9.1%) were HBeAg positive and 14/267 (5.2%) had a viral load of > 200 000 IU/mL. Ninety-eight (36.3%) HBsAg-positive women were HIV coinfected, 97 of whom were receiving antiretroviral treatment with tenofovir. Among HIV-negative women, four had an indication for tenofovir treatment and four for tenofovir PMTCT. Of 217 exposed liveborn babies, 181 (83.4%) received birth-dose HBV vaccine, 160 (88.4%) of these < 24 hours after birth. At the 9-month follow-up, only one out of the 134 tested infants was HBV positive.
conclusionOur nurse-led intervention highlights the feasibility of integrating PMTCT of HBV into existing antenatal care departments, essential for the implementation of the triple elimination initiative. Universal birth-dose vaccination is key to achieving HBV elimination.
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