Evidence map›Paper›PMID 35017259›Full record

ArticleeNeuro

Oxytocin Facilitates Allomaternal Behavior under Stress in Laboratory Mice.

Yousuke Tsuneoka, Chihiro Yoshihara, Ryuko Ohnishi, Sachine Yoshida, Eri Miyazawa, Masanobu Yamada, Kazuhiko Horiguchi, W Scott Young, Katsuhiko Nishimori, Tadafumi Kato and 1 more

Open access · goldAbstract read
In one paragraph

Article in eNeuro. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
6.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.

  1. Pooled it
  2. Neural circuits for mammalian parental behaviour.Nature reviews. Neuroscience · 2026
    Review
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  14. Maternal physiological calming responses to infant suckling at the breast.The journal of physiological sciences : JPS · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 2 countries.

Yousuke TsuneokaLaboratory for Affiliative Social Behavior, RIKEN Center for Brain Science, Wako 351-0198, Japan.
Chihiro YoshiharaLaboratory for Affiliative Social Behavior, RIKEN Center for Brain Science, Wako 351-0198, Japan.
Ryuko OhnishiLaboratory for Affiliative Social Behavior, RIKEN Center for Brain Science, Wako 351-0198, Japan.
Sachine YoshidaLaboratory for Affiliative Social Behavior, RIKEN Center for Brain Science, Wako 351-0198, Japan.
Eri MiyazawaLaboratory for Affiliative Social Behavior, RIKEN Center for Brain Science, Wako 351-0198, Japan.
Masanobu YamadaDepartment of Internal Medicine, Division of Endocrinology and Metabolism, Gunma University Graduate School of Medicine, Maebashi 371-8511, Japan.
Kazuhiko HoriguchiDepartment of Internal Medicine, Division of Endocrinology and Metabolism, Gunma University Graduate School of Medicine, Maebashi 371-8511, Japan.
W Scott YoungSection on Neural Gene Expression, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892-9663.
Katsuhiko NishimoriDepartment of Obesity and Internal Inflammation, Fukushima Medical University, Fukushima 960-1295, Japan.
Tadafumi KatoDepartment of Psychiatry and Behavioral Science, Graduate School of Medicine, Juntendo University, Tokyo 113-0033, Japan.
Kumi O KurodaLaboratory for Affiliative Social Behavior, RIKEN Center for Brain Science, Wako 351-0198, Japan kumi.kuroda@riken.jp.
RIKEN Center for Brain Science · JPGunma University · JPFukushima Medical University · JPJuntendo University · JPNational Institutes of Health · US

Funding

Roles of Oxytocin and Vasopressin in BrainZIAMH002498 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI YOUNG, WALTER SCOTT · 2009 to 2022
$26.3M
6 · The paper itself

Abstract

Oxytocin (Oxt) controls reproductive physiology and various kinds of social behaviors, but the exact contribution of Oxt to different components of parental care still needs to be determined. Here, we illustrate the neuroanatomical relations of the parental nurturing-induced neuronal activation with magnocellular Oxt neurons and fibers in the medial preoptic area (MPOA), the brain region critical for parental and alloparental behaviors. We used genetically-targeted mouse lines for

Indexed as

OxytocinReceptors, OxytocinAnimalsFemaleMaleMiceNeuronsParturitionPregnancySocial BehaviorOxytocinReceptors, Oxytocinmaternal behaviormedial preoptic areaMus musculusoxytocinvasopressin

Identifiers

PMID35017259
PMCPMC8868028
OpenAlexW4205192267

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.