SynthesisBMJ open2022
Problems with evidence assessment in COVID-19 health policy impact evaluation: a systematic review of study design and evidence strength.
Synthesis in BMJ open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it.
- A Systematic Review of Economic Evaluations of COVID-19 Interventions: Considerations of Non-Health Impacts and Distributional Issues.Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research · 2022Pooled it
- Informed decisions about public health and social measures.Health research policy and systems · 2025Review
- Post-pandemic mental health: Understanding the global psychological burden and charting future research priorities.World journal of psychiatry · 2025Review
- Difference-in-Differences for Health Policy and Practice: A Review of Modern Methods.Statistics in medicine · 2025Review
- Strengthening research preparedness for crises: lessons from Norwegian government agencies in using randomized trials and quasi-experimental methods to evaluate public policy interventions.Health research policy and systems · 2025Article
- A causal machine-learning framework for studying policy impact on air pollution: a case study in COVID-19 lockdowns.American journal of epidemiology · 2025Article
- Short, stringent lockdowns halted SARS-CoV-2 transmissions in Danish municipalities.Scientific reports · 2024Article
- Quasi-experimental methods for pharmacoepidemiology: difference-in-differences and synthetic control methods with case studies for vaccine evaluation.American journal of epidemiology · 2024Article
- US State Restrictions and Excess COVID-19 Pandemic Deaths.JAMA health forum · 2024Article
- The Ethical Obligation for Research During Public Health Emergencies: Insights From the COVID-19 Pandemic.Medicine, health care, and philosophy · 2024Article
- Policy evaluation during a pandemic.Journal of econometrics · 2023Article
- To vaccinate or to isolate? Establishing which intervention leads to measurable mortality reduction during the COVID-19 Delta wave in Poland.Frontiers in public health · 2023Article
- Go To Travel campaign and the geographic spread of COVID-19 in Japan.BMC infectious diseases · 2022Article
- Reflections on the COVID-19 pandemic.Journal of paediatrics and child health · 2022Article
- Pandemics, policy, and the power of paradigm: will COVID-19 lead to a new scientific revolution?Annals of epidemiology · 2022Article
- The Impact of Keeping Indoor Dining Closed on COVID-19 Rates Among Large US Cities: A Quasi-Experimental Design.Epidemiology (Cambridge, Mass.) · 2022Article
- COVID-19 data are messy: analytic methods for rigorous impact analyses with imperfect data.Globalization and health · 2022Review
- Moving beyond the classic difference-in-differences model: a simulation study comparing statistical methods for estimating effectiveness of state-level policies.BMC medical research methodology · 2021Article
- Much ado about something: a response to "COVID-19: underpowered randomised trials, or no randomised trials?"Trials · 2021Article
Corrections and comments
- Update of
Authors and funding
24 authors.
Funding
Abstract
introductionAssessing the impact of COVID-19 policy is critical for informing future policies. However, there are concerns about the overall strength of COVID-19 impact evaluation studies given the circumstances for evaluation and concerns about the publication environment.
methodsWe included studies that were primarily designed to estimate the quantitative impact of one or more implemented COVID-19 policies on direct SARS-CoV-2 and COVID-19 outcomes. After searching PubMed for peer-reviewed articles published on 26 November 2020 or earlier and screening, all studies were reviewed by three reviewers first independently and then to consensus. The review tool was based on previously developed and released review guidance for COVID-19 policy impact evaluation.
resultsAfter 102 articles were identified as potentially meeting inclusion criteria, we identified 36 published articles that evaluated the quantitative impact of COVID-19 policies on direct COVID-19 outcomes. Nine studies were set aside because the study design was considered inappropriate for COVID-19 policy impact evaluation (n=8 pre/post; n=1 cross-sectional), and 27 articles were given a full consensus assessment. 20/27 met criteria for graphical display of data, 5/27 for functional form, 19/27 for timing between policy implementation and impact, and only 3/27 for concurrent changes to the outcomes. Only 4/27 were rated as overall appropriate. Including the 9 studies set aside, reviewers found that only four of the 36 identified published and peer-reviewed health policy impact evaluation studies passed a set of key design checks for identifying the causal impact of policies on COVID-19 outcomes. DISCUSSION: The reviewed literature directly evaluating the impact of COVID-19 policies largely failed to meet key design criteria for inference of sufficient rigour to be actionable by policy-makers. More reliable evidence review is needed to both identify and produce policy-actionable evidence, alongside the recognition that actionable evidence is often unlikely to be feasible.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.