Evidence map›Paper›PMID 35017189›Full record

Observational studyEmergency medicine journal : EMJ2022

The association between vital signs and clinical outcomes in emergency department patients of different age categories.

Bart Gj Candel, Renée Duijzer, Menno I Gaakeer, Ewoud Ter Avest, Özcan Sir, Heleen Lameijer, Roger Hessels, Resi Reijnen, Erik W van Zwet, Evert de Jonge and 1 more

Abstract readObservational Study
In one paragraph

Observational study in Emergency medicine journal : EMJ, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

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  11. Diagnostic and therapeutic management of severe acute pancreatitis. Evidence based medicine (EBM) clinical practice guidelines.Wideochirurgia i inne techniki maloinwazyjne = Videosurgery and other miniinvasive techniques · 2025
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  20. Pathophysiological Features in Electronic Medical Records Sustain Model Performance under Temporal Dataset Shift.AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Bart Gj CandelEmergency Department, Maxima Medical Centre, Veldhoven, Noord-Brabant, The Netherlands bart.candel@mmc.nl.ORCID http://orcid.org/0000-0002-4500-9960
Renée DuijzerEmergency Department, Leiden University Medical Centre, Leiden, Zuid-Holland, The Netherlands.
Menno I GaakeerEmergency Department, Admiraal De Ruyter Hospital, Goes, Zeeland, The Netherlands.
Ewoud Ter AvestEmergency Department, University Medical Centre Groningen, Groningen, The Netherlands.ORCID http://orcid.org/0000-0002-1462-6130
Özcan SirEmergency Department, Radboud University Medical Centre, Nijmegen, The Netherlands.
Heleen LameijerEmergency Department, Medical Centre Leeuwarden, Leeuwarden, Friesland, The Netherlands.ORCID http://orcid.org/0000-0001-9378-7743
Roger HesselsEmergency Department, Elisabeth-TweeSteden Hospital, Tilburg, Noord-Brabant, The Netherlands.
Resi ReijnenEmergency Department, Medical Centre Haaglanden, Den Haag, Zuid-Holland, The Netherlands.
Erik W van ZwetDepartment of Biostatistics, Leiden Universitair Medical Centre, Leiden, Zuid-Holland, The Netherlands.
Evert de JongeIntensive Care, Leiden University Medical Centre, Leiden, Zuid-Holland, The Netherlands.
Bas de GrootEmergency Department, Leiden University Medical Centre, Leiden, Zuid-Holland, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAppropriate interpretation of vital signs is essential for risk stratification in the emergency department (ED) but may change with advancing age. In several guidelines, risk scores such as the Systemic Inflammatory Response Syndrome

aimsTo assess the association between initial vital signs and case-mix adjusted in-hospital mortality in different age categories.

methodsObservational multicentre cohort study using the Netherlands Emergency Department Evaluation Database (NEED) in which consecutive ED patients ≥18 years were included between 1 January 2017 and 12 January 2020. The association between vital signs and case-mix adjusted mortality were assessed in three age categories (18-65; 66-80; >80 years) using multivariable logistic regression. Vital signs were each divided into five to six categories, for example, systolic blood pressure (SBP) categories (≤80, 81-100, 101-120, 121-140, >140 mm Hg).

resultsWe included 101 416 patients of whom 2374 (2.3%) died. Adjusted ORs for mortality increased gradually with decreasing SBP and decreasing peripheral oxygen saturation (SpO

conclusionFor SBP, DBP, SpO

Indexed as

Emergency Service, HospitalVital SignsAgedCohort StudiesHospital MortalityHumansPrognosisRetrospective StudiesSystemic Inflammatory Response Syndromeemergency departmentgeriatricsrisk managementtriage

Identifiers

PMID35017189
PMCPMC9691829

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.