ReviewEmergency medicine journal : EMJ2022
Point-of-care testing with high-sensitivity cardiac troponin assays: the challenges and opportunities.
Review in Emergency medicine journal : EMJ, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 62 citations in OpenAlex.
- Article
- Deep learning-enhanced dual-mode multiplexed optical sensor for point-of-care diagnostics of cardiovascular diseases.Light, science & applications · 2026Article
- Development of a High-Sensitivity Electrochemical Immunoassay Using a Fully 3D-Printed Electrocatalytic Microelectrode Probe Platform.Analytical chemistry · 2026Article
- Potential impact of a point-of-care high-sensitivity cardiac troponin assay on emergency department length of stay and patient disposition: findings from a cardiac emergency department.Emergency medicine journal : EMJ · 2025Article
- Cardiac troponin at the point of care in acute and chronic coronary syndromes.Diabetes, obesity & metabolism · 2025Review
- Cardiac Troponin I Biosensors: Innovations in Real-Time Diagnosis of Cardiovascular Diseases.Analytical science advances · 2025Review
- A High-Sensitivity Troponin I Rapid Assay vs. a High-Sensitivity Troponin T Routine Assay in Acute Chest Pain Patients: A Prospective Monocentric Study.Journal of clinical medicine · 2025Article
- Article
- Cardiac Troponin as a Prognostic Indicator for Major Adverse Cardiac Events in Non-Cardiac Surgery: A Narrative Review.Diagnostics (Basel, Switzerland) · 2025Review
- Potential length of stay reductions from emergency department use of a point-of-care high-sensitivity cardiac troponin assay: Pilot findings from Australia's first cardiac emergency department.Emergency medicine Australasia : EMA · 2025Article
- Deep Learning-Enhanced Chemiluminescence Vertical Flow Assay for High-Sensitivity Cardiac Troponin I Testing.Small (Weinheim an der Bergstrasse, Germany) · 2025Article
- Patient-centred newer testing methods for major cardiac disorders.Indian journal of thoracic and cardiovascular surgery · 2025Review
- Emergency department use of a high-sensitivity point-of-care troponin assay reduces length of stay: an implementation study preliminary report.European heart journal. Acute cardiovascular care · 2024Article
- Article
- Point of care testing for high-sensitive troponin measurement: experience from a tertiary care hospital clinical laboratory.Advances in laboratory medicine · 2024Article
- Deep Learning-Enhanced Paper-Based Vertical Flow Assay for High-Sensitivity Troponin Detection Using Nanoparticle Amplification.ACS nano · 2024Article
- Article
- A Portable Readout System for Biomarker Detection with Aptamer-Modified CMOS ISFET Array.Sensors (Basel, Switzerland) · 2024Article
- Review
- Clinical Biochemistry of Serum Troponin.Diagnostics (Basel, Switzerland) · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Methods to improve the safety, accuracy and efficiency of assessment of patients with suspected acute coronary symptoms have occupied decades of study and have supported significant changes in clinical practice. Much of the progress is reliant on results of laboratory-based high-sensitivity cardiac troponin assays that can detect low concentrations with high precision. Until recently, point-of-care (POC) platforms were unable to perform with similar analytical precision as laboratory-based assays, and recommendations for their use in accelerated assessment strategies for patients with suspected acute coronary syndrome has been limited. As POC assays can provide troponin results within 20 min, and can be used proximate to patient care, improvements in the efficiency of assessment of patients with suspected acute coronary syndrome is possible, particularly with new high-sensitivity assays.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.