Evidence map›Paper›PMID 35017177›Full record

ReviewPharmacological reviews2022

Therapeutics in the Pipeline Targeting

Hilary Grosso Jasutkar, Stephanie E Oh, M Maral Mouradian

Open access · bronzeAbstract readReview
In one paragraph

Review in Pharmacological reviews, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed
10.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

52 citing papers in PubMed, 88 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. 8-Gingerol Mitigates MPPNeurochemical research · 2026
    Article
  6. Progress of Immunotherapies in Parkinson's Disease.CNS neuroscience & therapeutics · 2026
    Review
  7. Review
  8. Article
  9. Review
  10. Review
  11. Review
  12. Neuroprotection in Parkinson Disease.Neurology and therapy · 2025
    Review
  13. Article
  14. Review
  15. Review
  16. Global kinetic model of lipid-inducedProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  17. Review
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Hilary Grosso JasutkarRobert Wood Johnson Medical School Institute for Neurological Therapeutics, and Department of Neurology, Rutgers Biomedical and Health Sciences, Piscataway, New Jersey.
Stephanie E OhRobert Wood Johnson Medical School Institute for Neurological Therapeutics, and Department of Neurology, Rutgers Biomedical and Health Sciences, Piscataway, New Jersey.
M Maral MouradianRobert Wood Johnson Medical School Institute for Neurological Therapeutics, and Department of Neurology, Rutgers Biomedical and Health Sciences, Piscataway, New Jersey m.mouradian@rutgers.edu.
Rutgers HealthRutgers, The State University of New Jersey · US

Funding

PP2A Dysregulation in the Pathogenesis of alpha-SynucleinopathiesR01NS101134 · NINDS · RBHS-ROBERT WOOD JOHNSON MEDICAL SCHOOL · PI MOURADIAN, M. MARAL, NICHOLLS, RUSSELL E · 2017 to 2021
$2.3M
Synergistic Neuroprotective Mechanisms of Coffee Components in Parkinson's DiseasR01AT006868 · NCCIH · UNIV OF MED/DENT NJ-R W JOHNSON MED SCH · PI MOURADIAN, M. MARAL, STOCK, JEFFRY B · 2012 to 2016
$2.2M
RNA Targeted Drug Discovery and Development for Parkinson DiseaseUH3NS116921 · NINDS · RBHS-ROBERT WOOD JOHNSON MEDICAL SCHOOL · PI DISNEY, MATTHEW D, MOURADIAN, M. MARAL · 2021 to 2021
$851k
Developing Novel RNA-Based Therapeutics for Parkinson's DiseaseR33NS096032 · NINDS · RBHS-ROBERT WOOD JOHNSON MEDICAL SCHOOL · PI DISNEY, MATTHEW D, MOURADIAN, M. MARAL · 2018 to 2019
$843k
RNA Targeted Drug Discovery and Development for Parkinson DiseaseUG3NS116921 · NINDS · RBHS-ROBERT WOOD JOHNSON MEDICAL SCHOOL · PI DISNEY, MATTHEW D, MOURADIAN, M. MARAL · 2020 to 2020
$523k
Developing Novel RNA-Based Therapeutics for Parkinson's DiseaseR21NS096032 · NINDS · RBHS-ROBERT WOOD JOHNSON MEDICAL SCHOOL · PI DISNEY, MATTHEW D, MOURADIAN, M. MARAL · 2017 to 2017
$452k
Role of Transglutaminase 2 in SynucleinopathiesR21NS123770 · NINDS · RBHS-ROBERT WOOD JOHNSON MEDICAL SCHOOL · PI MOURADIAN, M. MARAL · 2021 to 2021
$432k
NCCIH NIH HHS R01 AT006868NINDS NIH HHS R01 NS101134NINDS NIH HHS R21 NS096032NINDS NIH HHS R21 NS123770NINDS NIH HHS R33 NS096032NINDS NIH HHS UG3 NS116921NINDS NIH HHS UH3 NS116921
6 · The paper itself

Abstract

Parkinson's disease (PD) is the second most common neurodegenerative disorder and the fastest growing neurologic disease in the world, yet no disease-modifying therapy is available for this disabling condition. Multiple lines of evidence implicate the protein

Indexed as

Neurodegenerative DiseasesParkinson Diseasealpha-SynucleinBrainHumansLewy Bodiesalpha-Synuclein

Identifiers

PMID35017177
PMCPMC11034868
OpenAlexW4206464678

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.