Evidence map›Paper›PMID 35017050›Full record

ArticleThe Journal of arthroplasty2022

Staging Bilateral Total Knee Arthroplasties Reduces Alignment Outliers.

Matthew A Follett, Prerna Arora, William J Maloney, Stuart B Goodman, James I Huddleston, Derek F Amanatullah

Abstract read
In one paragraph

Article in The Journal of arthroplasty, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Matthew A FollettDepartment of Orthopaedic Surgery, Stanford Medicine, Redwood City, CA.
Prerna AroraDepartment of Orthopaedic Surgery, Stanford Medicine, Redwood City, CA.
William J MaloneyDepartment of Orthopaedic Surgery, Stanford Medicine, Redwood City, CA.
Stuart B GoodmanDepartment of Orthopaedic Surgery, Stanford Medicine, Redwood City, CA.
James I HuddlestonDepartment of Orthopaedic Surgery, Stanford Medicine, Redwood City, CA.
Derek F AmanatullahDepartment of Orthopaedic Surgery, Stanford Medicine, Redwood City, CA.

Funding

Institutional Career Development Core (KL2)KL2TR003143 · NCATS · STANFORD UNIVERSITY · PI ASCH, STEVEN M. · 2019 to 2023
$8.7M
NCATS NIH HHS KL2 TR003143
6 · The paper itself

Abstract

backgroundPatients frequently present with bilateral symptomatic knee osteoarthritis and request simultaneous total knee arthroplasties (TKAs). Technical differences between simultaneous and staged TKAs could affect clinical and radiographic outcomes. We hypothesized that staged TKAs would have fewer mechanical alignment outliers than simultaneous TKAs.

methodsWe reviewed 87 simultaneous and 72 staged TKAs with at least 2 years of follow-up. Radiographic assessment was done using standing long leg and lateral radiographs of the knee. Coronal and sagittal measurements were performed by 4 blinded observers on 2 separate occasions with an intraobserver agreement of 0.95 and interobserver of 0.92.

resultsThe first simultaneous knee had no difference in the probability of establishing the mechanical axis outside 3° of neutral (45%) compared to the first staged knee (54%, P = .337). However, the second simultaneous knee (49%) was more likely to establish the axis outside mechanical neutral compared to the second staged knee (28%; odds ratio 2.54, confidence interval 1.31-4.94, P = .006). There was an increased risk of deep venous thrombosis with staged TKA (odds ratio 2.96, confidence interval 1.28-6.84, P = .011), but other perioperative complication rates were not significantly different. There were no clinically significant differences in range of motion or Knee Society Score.

conclusionThere is a significantly increased risk of establishing the second knee outside mechanical neutral during a simultaneous TKA compared to staged bilateral TKAs, possibly related to a number of surgeon-related and system-related factors. The impact on clinical outcomes and radiographic loosening may become significant in long-term follow-up.

Indexed as

Arthroplasty, Replacement, KneeOsteoarthritis, KneeHumansKnee JointRange of Motion, ArticularRetrospective StudiesTreatment Outcomemechanical alignmentsimultaneous total knee arthroplastystaged total knee arthroplastytotal knee arthroplasty alignment outlierstotal knee arthroplasty outcomes

Identifiers

PMID35017050
PMCPMC8934296

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.