Evidence map›Paper›PMID 35017011›Full record

ArticleResuscitation2022

Physicians' cognitive approach to prognostication after cardiac arrest.

Alexis Steinberg, Emily Grayek, Robert M Arnold, Clifton Callaway, Baruch Fischhoff, Tamar Krishnamurti, Deepika Mohan, Douglas B White, Jonathan Elmer

Registry-linked trialAbstract read
In one paragraph

Article in Resuscitation, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07002294 (The Effect of SPecialty cAre on Recovery From Cardiac Arrest Trial), which is not on this map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07002294 narecruitingnot on this mapstarted 2026, after this paper: background citation

The Effect of SPecialty cAre on Recovery From Cardiac Arrest Trial (the SPARC Trial)

TypeinterventionalSponsorUniversity of PittsburghRan2026 to 2032Enrolled1,618ConditionsCardiac Arrest (CA), Heart Arrest, Heart Arrest, Out-Of-HospitalArmsTransfer to specialty care, Usual care
3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Real-Time Assessment of Factors Impacting Prognostic Predictions After Pediatric Cardiac Arrest: A Single-Center Prospective Study.Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies · 2026
    Observational
  3. Article
  4. Review
  5. Review
  6. Timing of neuroprognostication in the ICU.Current opinion in critical care · 2025
    Review
  7. Article
  8. Neurological diseases in intensive care.Intensive care medicine · 2023
    Article
  9. Article
  10. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Alexis SteinbergDepartment of Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA; Department of Neurology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA; Department of Emergency Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA. Electronic address: Steinberga2@upmc.edu.
Emily GrayekDepartment of Engineering and Public Policy, Carnegie Mellon University, Pittsburgh, PA, USA.
Robert M ArnoldSection of Palliative Care and Medical Ethics, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Clifton CallawayDepartment of Emergency Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Baruch FischhoffDepartment of Engineering and Public Policy, Carnegie Mellon University, Pittsburgh, PA, USA; Institute for Politics and Strategy, Carnegie Mellon University, Pittsburgh, PA, USA.
Tamar KrishnamurtiDepartment of General Internal Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Deepika MohanDepartment of Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA; Department of Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Douglas B WhiteProgram on Ethics and Decision Making in Critical Illness, Department of Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Jonathan ElmerDepartment of Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA; Department of Neurology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA; Department of Emergency Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.

Funding

Quantitative electroencephalography after cardiac arrestK23NS097629 · NINDS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI ELMER, JONATHAN · 2017 to 2021
$945k
Mentored Patient Oriented Research in Improving Surrogate Decision Making for Patients with Advanced Respiratory FailureK24HL148314 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Douglas B White · 2019 to 2026
$944k
NHLBI NIH HHS K24 HL148314NINDS NIH HHS K23 NS097629
6 · The paper itself

Abstract

objectiveElucidate how physicians formulate a neurological prognosis after cardiac arrest and compare differences between experts and general providers.

methodsWe performed semi-structured interviews with experts in post-arrest care and general physicians. We created an initial model and interview guide based on professional society guidelines. Two authors independently coded interviews based on this initial model, then identified new topics not included in it. To describe individual physicians' cognitive approach to prognostication, we created a graphical representation. We summarized these individual "mental models" into a single overall model, as well as two models stratified by expertise.

resultsWe performed 36 interviews (17 experts and 19 generalists), most of whom practice in Europe (23) or North America (12). Participants described their approach to prognosis formulation as complex and iterative, with sequential and repeated data acquisition, interpretation, and prognosis formulation. Eventually, this cycle results in a final prognosis and treatment recommendation. Commonly mentioned factors were diagnostic test performance, time from arrest, patient characteristics. Participants also discussed factors rarely discussed in prognostication research including physician and hospital characteristics. We found no substantial differences between experts and general physicians.

conclusionPhysicians' cognitive approach to neurologic prognostication is complex and influenced by many factors, including some rarely considered in current research. Understanding these processes better could inform interventions designed to aid physicians in prognostication.

Indexed as

Heart ArrestPhysiciansCognitionEuropeHumansPrognosisCardiac arrestDecision-makingHypoxic-ischemic injuryPrognostication

Identifiers

PMID35017011
PMCPMC8983442

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.