Evidence map›Paper›PMID 35016785›Full record

ArticleGynecologic oncology2022

Distress screening in endometrial cancer leads to disparity in referral to support services.

Hadley W Reid, Gloria Broadwater, Mary Katherine Montes de Oca, Bharathi Selvan, Oluwadamilola Fayanju, Laura J Havrilesky, Brittany A Davidson

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Gynecologic oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Patient-Reported Distress in Individuals With Head and Neck Cancer.JAMA otolaryngology-- head & neck surgery · 2025
    Article
  3. Review
  4. Review
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Hadley W ReidDuke University School of Medicine, DUMC 3710, Durham, NC 27710, USA. Electronic address: hadley.reid@duke.edu.
Gloria BroadwaterDuke Cancer Institute Biostatistics, Duke University Medical Center, DUMC Box 2717, Durham, NC, USA. Electronic address: gloria.broadwater@duke.edu.
Mary Katherine Montes de OcaDepartment of Obstetrics and Gynecology, Duke University School of Medicine, 2608 Erwin Rd, STE 210, Durham, NC 27710, USA. Electronic address: mary.montes.de.oca@duke.edu.
Bharathi SelvanDuke University School of Medicine, DUMC 3710, Durham, NC 27710, USA. Electronic address: Bharathi.selvan@duke.edu.
Oluwadamilola FayanjuDepartment of Surgery, Duke University School of Medicine, DUMC 3513, Durham, NC 27710, USA. Electronic address: oluwadamilola.fayanju@pennmedicine.upenn.edu.
Laura J HavrileskyDivision of Gynecologic Oncology, Duke University School of Medicine, DUMC Box 3079, Durham, NC, 27710, USA. Electronic address: laura.havrilesky@duke.edu.
Brittany A DavidsonDivision of Gynecologic Oncology, Duke University School of Medicine, DUMC Box 3079, Durham, NC, 27710, USA. Electronic address: brittany.davidson@duke.edu.

Funding

NRSA Training CoreTL1TR002555 · NCATS · DUKE UNIVERSITY · PI EDELMAN, DAVID · 2018 to 2022
$3.7M
Using Modifiable Risk Factors to Predict Inferior Care and Survival after Breast Cancer Diagnosis: A Novel Approach to Addressing Health DisparitiesK08CA241390 · NCI · UNIVERSITY OF PENNSYLVANIA · PI FAYANJU, OLUWADAMILOLA M. · 2019 to 2023
$1.1M
NCATS NIH HHS TL1 TR002555NCI NIH HHS K08 CA241390
6 · The paper itself

Abstract

objectivesRacial disparities in survival from endometrial cancer (EC) are well known. Cancer distress has also been associated with worse clinical outcomes. We characterized the association between race/ethnicity, patient distress reported on the National Comprehensive Cancer Network Distress Thermometer and Problem List (NCCN DT & PL), referral to support services, time to surgery, and acceptance of adjuvant therapy in patients with EC.

methodsWe included patients presenting at an academic gynecologic oncology practice from 1/2013-6/2020 who had not received prior EC-directed treatment. Demographics, NCCN DT scores, and treatment details were abstracted from the electronic medical record. Difference in initial DT scores by race/ethnicity and treatment type was tested using general linear modeling. The significance of interaction effects was tested using linear mixed models and logistic regression.

results393 non-Hispanic White (NHW) and 134 non-Hispanic Black (NHB) patients were included. Median distress scores were higher in NHW patients compared to NHB patients (4 vs. 2, p < 0.001); 51% of NHW patients qualified for referral to support services compared to 40% of NHB patients (p = 0.03). Distress scores were highest at initial appointment and declined over time in NHW patients regardless of treatment, but were initially low and remained low over time in NHB patients. There was no association of initial distress score with time to surgery or acceptance of adjuvant treatment (p-values >0.25).

conclusionsAn observed difference in NCCN DT leads to racial disparities in referral to support services. The NCCN DT may not adequately measure distress in NHB women with EC.

Indexed as

Early Detection of CancerEndometrial NeoplasmsEthnicityFemaleHumansMass ScreeningReferral and ConsultationCancer distressEndometrial cancerHealth equityScreeningSupport services

Identifiers

PMID35016785
PMCPMC8891066

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.