Evidence map›Paper›PMID 35016733›Full record

ArticleJournal of cannabis research2022

A mixed methods analysis of cannabis use routines for chronic pain management.

Kevin F Boehnke, Laura Yakas, J Ryan Scott, Melissa DeJonckheere, Evangelos Litinas, Suzanne Sisley, Daniel J Clauw, David A Williams, Jenna McAfee

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of cannabis research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 19 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. The Elusive Truth of Cannabinoids for Rheumatic Pain.Current rheumatology reports · 2024
    Review
  5. Article
  6. Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Kevin F BoehnkeAnesthesiology Department, University of Michigan Medical School, Ann Arbor, MI, USA. kboehnke@med.umich.edu.ORCID http://orcid.org/0000-0003-3696-3979
Laura YakasAnesthesiology Department, University of Michigan Medical School, Ann Arbor, MI, USA.
J Ryan ScottAnesthesiology Department, University of Michigan Medical School, Ann Arbor, MI, USA.
Melissa DeJonckheereDepartment of Family Medicine, University of Michigan Medical School, Ann Arbor, MI, USA.
Evangelos LitinasIndependent Cannabis Consultant, Ann Arbor, MI, USA.
Suzanne SisleyScottsdale Research Institute, Phoenix, AZ, USA.
Daniel J ClauwAnesthesiology Department, University of Michigan Medical School, Ann Arbor, MI, USA.
David A WilliamsAnesthesiology Department, University of Michigan Medical School, Ann Arbor, MI, USA.
Jenna McAfeeAnesthesiology Department, University of Michigan Medical School, Ann Arbor, MI, USA.
University of Michigan · USAnn Arbor Center for Independent Living · USScottsdale Research Institute (United States) · US

Funding

University of Michigan's TMJD and Orofacial Pain Interdisciplinary ConsortiumK12DE023574 · NIDCR · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI CLAUW, DANIEL J, KAPILA, SUNIL D · 2013 to 2017
$1.8M
Cannabinoid Effects on Sleep and Pain Mechanisms in Osteoarthritis of the KneeK01DA049219 · NIDA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI BOEHNKE, KEVIN FOXMAN · 2020 to 2023
$569k
NIDA NIH HHS K01 DA049219NIDCR NIH HHS Grant No. K12DE023574NIDCR NIH HHS K12 DE023574
6 · The paper itself

Abstract

backgroundThe wide heterogeneity of available cannabis products makes it difficult for physicians to appropriately guide patients. In the current study, our objective was to characterize naturalistic cannabis use routines and explore associations between routines and reported benefits from consuming cannabis.

methodsWe performed a mixed methods analysis of n=1087 cross-sectional survey responses from adults with self-reported chronic pain using cannabis for symptom management in the USA and Canada. First, we qualitatively analyzed responses to an open-ended question that assessed typical cannabis use routines, including administration routes, cannabinoid content, and timing. We then sub-grouped responses into categories based on inhalation (smoking, vaporizing) vs. non-inhalation (e.g., edibles). Finally, we investigated subgroups perceptions of how cannabis affected pain, overall health, and use of medications (e.g., substituting for opioids, benzodiazepines). Substitutions were treated as a count of medication classes, while responses for both pain and health were analyzed continuously, with - 2 indicating health declining a lot or pain increasing a lot and 2 indicating that health improved a lot or pain decreased a lot.

resultsRoutines varied widely in terms of administration routes, cannabinoid content, and use timing. Overall, 18.8%, 36.2%, and 45% used non-inhalation, inhalation, and non-inhalation + inhalation routes, respectively. Those who used inhalation routes were younger (mean age 46.5 [inhalation] and 49.2 [non-inhalation + inhalation] vs. 56.3 [inhalation], F=36.1, p<0.001), while a higher proportion of those who used non-inhalation routes were female (72.5% non-inhalation vs. 48.3% inhalation and 65.3% non-inhalation + inhalation, X

conclusionsSubgrouping medical cannabis patients based on administration route profile may provide useful categories for future studies examining the risks and benefits of medical cannabis.

Indexed as

Chronic painDosing regimenMedical cannabisMedication substitutionMixed methodsRoutes of administration

Identifiers

PMID35016733
PMCPMC8750808
OpenAlexW4206671240

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.