Evidence map›Paper›PMID 35016626›Full record

ArticleBMC ophthalmology2022

Axial length growth difference between eyes after monocular laser refractive surgery: eight patients who underwent myopic laser ablation for both eyes at intervals of several years.

Chenghai Weng, Fei Xia, Dang Xu, Xingtao Zhou, Liangcheng Wu

Abstract read
In one paragraph

Article in BMC ophthalmology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Chenghai Weng *Department of Ophthalmology, Jing-An District Center Hospital of Shanghai (Huashan Hospital Fudan University Jing-An Branch), Shanghai Medical College, Fudan University, No.259 Xikang Road, Shanghai, 200031, China.
Fei Xia *Eye Institute and Department of Ophthalmology, Eye & ENT Hospital, Fudan University, No.19 Baoqing Road, Shanghai, 200031, China.
Dang XuDepartment of Ophthalmology, Jing-An District Center Hospital of Shanghai (Huashan Hospital Fudan University Jing-An Branch), Shanghai Medical College, Fudan University, No.259 Xikang Road, Shanghai, 200031, China.
Xingtao ZhouEye Institute and Department of Ophthalmology, Eye & ENT Hospital, Fudan University, No.19 Baoqing Road, Shanghai, 200031, China.
Liangcheng WuDepartment of Ophthalmology, Jing-An District Center Hospital of Shanghai (Huashan Hospital Fudan University Jing-An Branch), Shanghai Medical College, Fudan University, No.259 Xikang Road, Shanghai, 200031, China. liangchengwu@aliyun.com.ORCID http://orcid.org/0000-0001-7606-7592

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMyopia is a global public health issue. Controlling myopia progression is a primary focus of myopia studies today. Peripheral retinal myopic defocus is considered the mechanism for reduced myopia progression in orthokeratology studies. The topographic change in the front corneal surface after laser refractive surgery and orthokeratology procedures may appear similar. The purpose of this study was to explore the role of myopic laser ablation on axial length (AL) growth.

methodsMyopic patients who underwent monocular excimer laser refractive surgery first in one eye and then in another eye several years later because of myopia occurrence or myopia progression were recruited. The axial length elongation and refraction (spherical equivalent) between the two eyes were observed and compared.

resultsA total of 8 myopic patients were enrolled in the study. The AL increased from 24.52 ± 0.96 mm to 24.68 ± 1.03 mm but without significance (T = 1.49, P > 0.05) in the ablated eyes. The AL increased significantly from 23.73 ± 0.91 mm to 24.26 ± 0.95 mm in the nonablated eyes (T = 6.76, P < 0.001). The AL elongation of the ablated eyes with 0.16 ± 0.30 mm growth was significantly lower than that of the nonablated eyes with 0.53 ± 0.32 mm growth (T = 8.98, P < 0.001). The spherical equivalent (SE) increased significantly in the ablated eyes (- 0.59 ± 0.21 (D), T = 6.36, P < 0.001) and in the nonablated eyes (- 0.97 ± 0.55 (D), T = 4.91, P < 0.01), and the difference between the two eyes was significant (T = 3.05, P < 0.05).

conclusionsThe inhibitory effect of myopic laser ablation on AL elongation reported in the limited case studies argues for animal research on its efficacy as a new intervention for myopia progression.

Indexed as

Laser TherapyMyopiaRefractive Surgical ProceduresAxial Length, EyeHumansLasers, ExcimerRefraction, OcularRetrospective Studies

Identifiers

PMID35016626
PMCPMC8753812

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.