Evidence map›Paper›PMID 35016231›Full record

ArticleEuropean journal of dentistry2022

Antiplaque Efficacy of a Novel Moringa oleifera Dentifrice: A Randomized Clinical Crossover Study.

Kimberly Duarte, Biju Thomas, Sudhir Rama Varma, Vinayak Kamath, Bhavya Shetty, Syed Kuduruthullah, Manjusha Nambiar

Registry-linked trialOpen access · hybridAbstract read
In one paragraph

Article in European journal of dentistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06905379 (Remineralization Efficacy of Moringa Oleifera Varnish Vs MI Varnish in Initial Carious Lesions Over 6 Months Follow Up), which is not on this map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06905379 nanot yet recruitingnot on this mapstarted 2025, after this paper: background citation

Remineralization Efficacy of Moringa Oleifera Varnish Vs MI Varnish in Initial Carious Lesions Over 6 Months Follow Up: a Randomized Controlled Clinical Trial

TypeinterventionalSponsorCairo UniversityRan2025 to 2026Enrolled40ConditionsWhite Spot Lesions [Initial Caries] on Smooth Surface of Tooth, Moringa OleiferaArmsMoringa Oleifera, Varnish
3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Effects ofNutrients · 2022
    Trial
  4. TheScientificWorldJournal · 2023
    Review
  5. Effect of herbal and nonherbal dentifrice on gingival health - A clinical study.Journal of advanced pharmaceutical technology & research · 2022
    Article
  6. Article
  7. Assessment ofJournal of oral biology and craniofacial research
    Article
  8. Efficacy of aJournal of advanced pharmaceutical technology & research
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 2 countries.

Kimberly DuarteDepartment of Periodontics, AB Shetty Memorial Institute of Dental Sciences, Nitte(DU), Mangalore, Karnataka, India.ORCID 0000-0001-6615-0544
Biju ThomasDepartment of Periodontics, AB Shetty Memorial Institute of Dental Sciences, Nitte(DU), Mangalore, Karnataka, India.ORCID 0000-0001-8908-1019
Sudhir Rama VarmaDepartment of Clinical Sciences, Center of Medical and Bio-Allied Health Sciences Research, Ajman University, Ajman, United Arab Emirates.ORCID 0000-0001-6793-9344
Vinayak KamathDepartment of Public Health Dentistry, Goa Dental College and Hospital, Bambolim, North Goa, India.ORCID 0000-0002-6483-291X
Bhavya ShettyDepartment of Periodontology, Faculty of Dental Science, Ramaiah University of Applied Sciences, Bengaluru, Karnataka, India.ORCID 0000-0001-8701-3864
Syed KuduruthullahDepartment of Basic and Medical Sciences, Center of Medical and Bio-Allied Health Sciences Research, Ajman University, Ajman, United Arab Emirates.ORCID 0000-0002-7418-5808
Manjusha NambiarDepartment of Periodontics, Sri Rajiv Gandhi College of Dental Sciences and Hospital, Banguluru, Karnataka, India.ORCID 0000-0002-9791-0558
Ajman University · AENitte University · INGoa Dental College and Hospital · INM S Ramaiah University of Applied Sciences · INSri Rajiv Gandhi College of Dental Sciences and Hospital · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe use of herbal dentifrices has grown exponentially over the years. They are categorically referred to as ethnomedicines. Various agents have been tried with contradicting findings based on phytopharmacological analysis. Miswak is one agent which has been used over the years. A novel MATERIALS AND

methodsThis randomized clinical crossover study included 20 subjects with mild to moderate gingivitis. The study was conducted over a total examination period of 20 days with a wash-out period of 2 weeks between the use of both the toothpastes. The plaque index and gingival index of the study subjects were recorded at the designated time intervals throughout the study period. STATISTICAL ANALYSIS: The data collected were entered on Microsoft Excel, and statistical analysis using SPSS software (SPSS version 28, IBM Corp, Armonk, New York, United States) was done. The statistical test used was the Wilcoxon signed-rank test. Moreover,

resultsThe results showed that the reduction in mean gingival index scores from baseline to day 3 was more statistically significant in the moringa-based dentifrice. Similarly, the plaque index scores showed statistically significant reduction following the use of the moringa-based dentifrice when compared with the miswak dentifrice. This study reveals that the moringa dentifrice is a safe and effective agent in reducing plaque accumulation and treating gingival inflammation.

conclusionThe current study aims to provide an insight into the possible role of moringa dentifrice as a possible adjunctive oral hygiene aid.

Identifiers

PMID35016231
PMCPMC9683899
OpenAlexW4205446399

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.