Evidence map›Paper›PMID 35016118›Full record

ArticlePsychiatry research2022

Geographical variation in hospitalization for psychosis associated with cannabis use and cannabis legalization in the United States: Submit to: Psychiatry Research.

Lauren V Moran, Erica S Tsang, Dost Ongur, John Hsu, May Y Choi

Open access · greenAbstract read
In one paragraph

Article in Psychiatry research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.3field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 20 citations in OpenAlex.

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  8. Acute Toxicity and Pharmacokinetic Profile of an EU-GMP-CertifiedPharmaceuticals (Basel, Switzerland) · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Lauren V MoranDivision of Psychotic Disorders, McLean Hospital, Belmont, MA; Harvard T.H. Chan School of Public Health, Boston MA; Department of Psychiatry, Harvard Medical School, Boston, MA. Electronic address: lmoran4@partners.org.
Erica S TsangHarvard T.H. Chan School of Public Health, Boston MA; Division of Medical Oncology, BC Cancer and University of British Columbia, Vancouver, British Columbia, Canada.
Dost OngurDivision of Psychotic Disorders, McLean Hospital, Belmont, MA; Department of Psychiatry, Harvard Medical School, Boston, MA.
John HsuMongan Institute, Massachusetts General Hospital, Boston, MA; Department of Medicine, Harvard Medical School, Boston, MA; Department of Health Care Policy, Harvard Medical School, Boston, MA.
May Y ChoiHarvard T.H. Chan School of Public Health, Boston MA; Division of Rheumatology, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.
McLean Hospital · USBC Cancer Agency · CAMassachusetts General Hospital · USUniversity of Calgary · CA

Funding

Randomized controlled trial of enhanced coordinated specialty care (CSC 2.0)P50MH115846 · NIMH · MCLEAN HOSPITAL · PI MIGUEL HERNAN · 2019 to 2026
$16.9M
Risk Factors for Psychosis and Mania with Prescription Amphetamine UseR01MH122427 · NIMH · MCLEAN HOSPITAL · PI SHINN, ANN KYUNGAH · 2020 to 2023
$2.8M
Risk of Psychosis with Prescription Stimulant UseK23MH110564 · NIMH · MCLEAN HOSPITAL · PI MORAN, LAUREN V · 2017 to 2020
$790k
NIMH NIH HHS K23 MH110564NIMH NIH HHS P50 MH115846NIMH NIH HHS R01 MH122427
6 · The paper itself

Abstract

The 2017 National Inpatient Sample database was utilized to investigate the association between cannabis legalization in the United States and hospitalizations for psychosis associated with cannabis use. We compared the odds of hospital discharges for psychosis associated with cannabis use in adults between the Pacific census division (where most states legalized recreational cannabis use) and other divisions using multivariable logistic regression, adjusting for confounders. We calculated a score for each census division representing cannabis legality as the population-weighted sum of state scores: 1=illegal or cannabidiol/low potency cannabis; 2= medical marijuana; and 3=recreational and medical marijuana legalized. Pearson's correlation coefficients (r) quantified the relationship between scores and the proportion of hospitalizations with psychosis associated with cannabis. In 2017, there were an estimated 129,070 hospital discharges for psychosis associated with cannabis use. The Pacific census division had significantly higher odds of discharges than other divisions (adjusted odds ratio 1.55; 95% confidence interval 1.25 - 1.93). There was a significant correlation between the cannabis legality score and proportion of hospital discharges for psychosis associated with cannabis use (r = 0.67, p<0.05). In conclusion, we observed a higher proportion of hospital discharges for psychosis associated with cannabis use in areas with more liberal cannabis legalization laws.

Indexed as

CannabisHallucinogensMedical MarijuanaPsychiatryPsychotic DisordersAdultCannabinoid Receptor AgonistsHospitalizationHumansUnited StatesCannabinoid Receptor AgonistsHallucinogensMedical MarijuanaCannabisLegalizationMarijuanaPsychosisSchizophrenia

Identifiers

PMID35016118
PMCPMC8833839
OpenAlexW4206137699

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.