Trial reportAmerican journal of respiratory and critical care medicine2022
Daily Exposure to Mild Intermittent Hypoxia Reduces Blood Pressure in Male Patients with Obstructive Sleep Apnea and Hypertension.
Trial report in American journal of respiratory and critical care medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
36 citing papers in PubMed, 2 syntheses or guidelines pooled it, 58 citations in OpenAlex.
- The hypoxic ventilatory response and arousal burden predict the magnitude of ventilatory long-term facilitation in humans with obstructive sleep apnoea.Experimental physiology · 2026Pooled it
- The hypoxic ventilatory response and hypoxic burden are predictors of the magnitude of ventilatory long-term facilitation in humans.The Journal of physiology · 2023Pooled it
- Moderate intermittent hypoxic conditioning to enhance vascular function and cardiorespiratory fitness in the elderly: A randomized controlled trial.Physiological reports · 2025Trial
- Cardiorespiratory Responses to Acute Intermittent Hypoxia in Humans With Chronic Spinal Cord Injury.Journal of neurotrauma · 2024Trial
- Beneficially Stressing the Peripheral Nervous System to Repair.International journal of molecular sciences · 2026Review
- Sleep apnoea and its consequences: from animal models to precision medicine.Sleep medicine · 2026Review
- Disruption of sphingolipid metabolism triggers lung vascular inflammation and aging-like changes under hypoxia through VDAC1-mediated mitochondrial DNA release.Apoptosis : an international journal on programmed cell death · 2026Article
- Review
- Effects of a 6-Week Intermittent Hypoxia-Hyperoxia Exposure Program on Blood Pressure, Respiratory Function, Cardiac Autonomic Nervous Activity and CRP Levels in Older Adults: A Randomized Clinical Trial.Sports (Basel, Switzerland) · 2026Article
- Combining exercise and hypoxia for brain health: from elite athlete altitude training camps to clinical applications.AIMS neuroscience · 2026Review
- Therapeutic hypoxia to protect and revive ischemic heart and brain.Military Medical Research · 2026Article
- Construction of a nomogram prediction model for obstructive sleep apnea combined with hypertension via polysomnography: a single-center retrospective study.European journal of medical research · 2025Article
- Management of Adult Obstructive Sleep Apnoea: Many Questions, Not Enough Answers!Journal of sleep research · 2025Review
- Hypoxia and Tissue Regeneration: Adaptive Mechanisms and Therapeutic Opportunities.International journal of molecular sciences · 2025Review
- Individualized Algorithm-Based Intermittent Hypoxia Improves Quality of Life in Patients Suffering from Long-Term Sequelae After COVID-19 Infection.Journal of clinical medicine · 2025Article
- Hypoxia as a medicine.Science translational medicine · 2025Review
- Mild intermittent hypoxia may improve autonomic dysfunction in persons living with spinal cord injury: a preliminary snapshot.Frontiers in neuroscience · 2025Article
- Mitigating Increased Cardiovascular Risk in Patients with Obstructive Sleep Apnea Using GLP-1 Receptor Agonists and SGLT2 Inhibitors: Hype or Hope?Biomedicines · 2024Review
- mTOR in the Development of Hypoxic Pulmonary Hypertension Associated with Cardiometabolic Risk Factors.International journal of molecular sciences · 2024Review
- [Reoxygenation improves reduced hypothalamic leptin responsiveness induced by intermittent hypoxia in obese rats].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2024Article
Corrections and comments
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- Commented on byReply to Chen2022
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
PubMed holds no abstract for this paper.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.