Evidence map›Paper›PMID 35015873›Full record

ArticleJournal of animal science2022

Pulmonary arterial pressure in fattened Angus steers at moderate altitude influences early postmortem mitochondria functionality and meat color during retail display.

Chaoyu Zhai, Lance C Li Puma, Adam J Chicco, Asma Omar, Robert J Delmore, Ifigenia Geornaras, Scott E Speidel, Tim N Holt, Milton G Thomas, R Mark Enns and 1 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of animal science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.1field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Chaoyu ZhaiDepartment of Animal Sciences, Colorado State University, Fort Collins, CO 80523, USA.ORCID 0000-0001-5148-4584
Lance C Li PumaDepartment of Biomedical Sciences, Colorado State University, Fort Collins, CO 80523, USA.
Adam J ChiccoDepartment of Biomedical Sciences, Colorado State University, Fort Collins, CO 80523, USA.
Asma OmarDepartment of Biomedical Sciences, Colorado State University, Fort Collins, CO 80523, USA.
Robert J DelmoreDepartment of Animal Sciences, Colorado State University, Fort Collins, CO 80523, USA.
Ifigenia GeornarasDepartment of Animal Sciences, Colorado State University, Fort Collins, CO 80523, USA.
Scott E SpeidelDepartment of Animal Sciences, Colorado State University, Fort Collins, CO 80523, USA.ORCID 0000-0003-0247-5096
Tim N HoltDepartment of Clinical Sciences, Colorado State University, Fort Collins, CO 80523, USA.
Milton G ThomasDepartment of Animal Sciences, Colorado State University, Fort Collins, CO 80523, USA.
R Mark EnnsDepartment of Animal Sciences, Colorado State University, Fort Collins, CO 80523, USA.
Mahesh N NairDepartment of Animal Sciences, Colorado State University, Fort Collins, CO 80523, USA.
Colorado State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pulmonary hypertension is a noninfectious disease of cattle at altitudes > 1524 m (5,000 ft). Mean pulmonary arterial pressures (PAP) are used as an indicator for pulmonary hypertension in cattle. High PAP cattle (≥50 mmHg) entering the feedlot at moderate elevations have lower feed efficiency as compared to low PAP cattle (< 50 mmHg). The impact of pulmonary arterial pressure on mitochondrial function, oxidative phosphorylation (OXPHOS) protein abundance, and meat color was examined using longissimus lumborum (LL) from high (98 ± 13 mmHg; n = 5) and low (41 ± 3 mmHg; n = 6) PAP fattened Angus steers (live weight of 588 ± 38 kg) during early postmortem period (2 and 48 h) and retail display (days 1 to 9), respectively. High PAP muscle had greater (P = 0.013) OXPHOS-linked respiration and proton leak-associated respiration than low PAP muscles at 2 h postmortem but rapidly declined to be similar (P = 0.145) to low PAP muscle by 48 h postmortem. OXPHOS protein expression was higher (P = 0.045) in low PAP than high PAP muscle. During retail display, redness, chroma, hue, ratio of reflectance at 630 and 580 nm, and metmyoglobin reducing activity decreased faster (P < 0.05) in high PAP steaks than low PAP. Lipid oxidation significantly increased (P < 0.05) in high PAP steaks but not (P > 0.05) in low PAP. The results indicated that high PAP caused a lower OXPHOS efficiency and greater fuel oxidation rates under conditions of low ATP demand in premortem beef LL muscle; this could explain the lower feed efficiency in high PAP feedlot cattle compared to low PAP counterparts. Mitochondrial integral function (membrane integrity or/and protein function) declined faster in high PAP than low PAP muscle at early postmortem. LL steaks from high PAP animals had lower color stability than those from the low PAP animals during simulated retail display, which could be partially attributed to the loss of muscle mitochondrial function at early postmortem by ROS damage in high PAP muscle.

Indexed as

AltitudeRed MeatAnimalsArterial PressureCattleColorMeatMitochondriaMuscle, Skeletalbeef colorlongissimus lumborummeat qualitymitochondrial functionpulmonary hypertension

Identifiers

PMID35015873
PMCPMC8846331
OpenAlexW4205543068

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.