Evidence map›Paper›PMID 35015870›Full record

ReviewJournal of burn care & research : official publication of the American Burn Association2022

Research Progress on Preparation, Mechanism, and Clinical Application of Nanofat.

Pengbing Ding, Enhang Lu, Guan Li, Yidan Sun, Wenhui Yang, Zhenmin Zhao

Abstract readReview
In one paragraph

Review in Journal of burn care & research : official publication of the American Burn Association, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Human Adipose Allograft Restores Volume Through Host-mediated Tissue Replacement.Plastic and reconstructive surgery. Global open · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Operational Standard for Tissue-Extracted Collagen Facial Injection Techniques.Clinical, cosmetic and investigational dermatology · 2026
    Article
  9. Therapeutic potential of adipose tissue in aesthetic medicine.World journal of experimental medicine · 2025
    Review
  10. Review
  11. Article
  12. Review
  13. Article
  14. Review
  15. Review
  16. Article
  17. Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Pengbing DingDepartment of Plastic Surgery, Peking University Third Hospital, Beijing, China.
Enhang LuDepartment of Plastic Surgery, Peking University Third Hospital, Beijing, China.
Guan LiDepartment of Plastic Surgery, Peking University Third Hospital, Beijing, China.
Yidan SunDepartment of Plastic Surgery, Peking University Third Hospital, Beijing, China.
Wenhui YangDepartment of Plastic Surgery, Peking University Third Hospital, Beijing, China.
Zhenmin ZhaoDepartment of Plastic Surgery, Peking University Third Hospital, Beijing, China.

Funding

Key Clinical Projects of Peking University Third Hospital Y62496-01National Natural Science Funder of China 81571925
6 · The paper itself

Abstract

Autologous adipose tissue is an ideal soft tissue filling material in theory, which has the advantages of easy access, comprehensive source, and high biocompatibility and is now widely used in clinical practice. Based on the above benefits of autologous fat, autologous fat grafting is an essential technique in plastic surgery. Conventional macrofat is used to improve structural changes after soft tissue damage or loss caused by various causes such as disease, trauma, or aging. Due to the large diameter of particles and to avoid serious complications such as fat embolism, blunt needles with larger diameters (2 mm) are required, making the macrofat grafting difficult to the deep dermis and subdermis. Nanofat grafting is a relatively new technology that has gained popularity in cosmetic surgery in recent years. Nanofat is produced by mechanical shuffling and filtration of microfat, which is harvested by liposuction. The harvesting and processing of nanofat are cost-effective as it does not require additional equipment or culture time. Unlike microfat, nanofat particles are too small to provide a notable volumizing effect. Studies have shown that nanofat contains abundant stromal vascular fraction cells and adipose-derived stem cells, which help reconstruct dermal support structures, such as collagen, and regenerate healthier, younger-looking skin. Moreover, the fluid consistency of nanofat allows application in tissue regeneration, such as scars, chronic wounds, and facial rejuvenation. This article reviews the current research progress on the preparation, mechanism, and clinical application of nanofat.

Indexed as

BurnsAdipocytesAdipose TissueFaceHumansRejuvenation

Identifiers

PMID35015870
PMCPMC9435497

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.