Evidence map›Paper›PMID 35015334›Full record

ArticleBJOG : an international journal of obstetrics and gynaecology2022

Cervical cancer and COVID-an assessment of the initial effect of the pandemic and subsequent projection of impact for women in England: A cohort study.

Jennifer M Davies, Alice Spencer, Sian Macdonald, Lucy Dobson, Emily Haydock, Holly Burton, Georgios Angelopoulos, Pierre Martin-Hirsch, Nick J Wood, Amudha Thangavelu and 10 more

Abstract read
In one paragraph

Article in BJOG : an international journal of obstetrics and gynaecology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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  10. The impact of the COVID-19 pandemic on incidence gap in screen-detectable cancers: a cohort study in Greater Poland, Poland.Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology · 2024
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

20 authors.

Jennifer M DaviesLiverpool Women's NHS Foundation Trust, Liverpool, UK.
Alice SpencerLiverpool Women's NHS Foundation Trust, Liverpool, UK.
Sian MacdonaldLiverpool Women's NHS Foundation Trust, Liverpool, UK.
Lucy DobsonLiverpool Women's NHS Foundation Trust, Liverpool, UK.ORCID 0000-0002-7437-2590
Emily HaydockLancashire Teaching Hospitals NHS Trust, Preston, UK.
Holly BurtonLancashire Teaching Hospitals NHS Trust, Preston, UK.
Georgios AngelopoulosLancashire Teaching Hospitals NHS Trust, Preston, UK.
Pierre Martin-HirschLancashire Teaching Hospitals NHS Trust, Preston, UK.
Nick J WoodLancashire Teaching Hospitals NHS Trust, Preston, UK.
Amudha ThangaveluLeeds Teaching Hospitals NHS Trust, Leeds, UK.
Richard HutsonLeeds Teaching Hospitals NHS Trust, Leeds, UK.
Sarika MunotLeeds Teaching Hospitals NHS Trust, Leeds, UK.
Marina FlynnHull University Teaching Hospitals NHS Trust, Hull, UK.
Michael SmithChristie NHS Foundation Trust, Manchester, UK.
Bridget DeCruzeChristie NHS Foundation Trust, Manchester, UK.
Eva MyriokefalitakiChristie NHS Foundation Trust, Manchester, UK.
Katelijn SapChristie NHS Foundation Trust, Manchester, UK.
Brett Winter-RoachChristie NHS Foundation Trust, Manchester, UK.
Robert MacdonaldLiverpool Women's NHS Foundation Trust, Liverpool, UK.
Richard J EdmondsonDivision of Cancer Sciences, Faculty of Biology, Medicine and Health, St Mary's Hospital, University of Manchester, Manchester, UK.ORCID 0000-0003-2553-4423

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo review the effect of the COVID-19 pandemic on the diagnosis of cervical cancer and model the impact on workload over the next 3 years.

designA retrospective, control, cohort study.

settingSix cancer centres in the North of England representing a combined population of 11.5 million.

methodsData were collected retrospectively for all diagnoses of cervical cancer during May-October 2019 (Pre-COVID cohort) and May-October 2020 (COVID cohort). Data were used to generate tools to forecast case numbers for the next 3 years.

main outcome measuresHistology, stage, presentation, onset of symptoms, investigation and type of treatment. Patients with recurrent disease were excluded.

results406 patients were registered across the study periods; 233 in 2019 and 173 in 2020, representing a 25.7% (n = 60) reduction in absolute numbers of diagnoses. This was accounted for by a reduction in the number of low stage cases (104 in 2019 to 77 in 2020). Adding these data to the additional cases associated with a temporary cessation in screening during the pandemic allowed development of forecasts, suggesting that over the next 3 years there would be 586, 228 and 105 extra cases of local, regional and distant disease, respectively, throughout England. Projection tools suggest that increasing surgical capacity by two or three cases per month per centre would eradicate this excess by 12 months and 7 months, respectively.

conclusionsThere is likely to be a significant increase in cervical cancer cases presenting over the next 3 years. Increased surgical capacity could mitigate this with little increase in morbidity or mortality. TWEETABLE ABSTRACT: Covid will result in 919 extra cases of cervical cancer in England alone. Effects can be mitigated by increasing surgical capacity.

Indexed as

COVID-19Uterine Cervical NeoplasmsCohort StudiesEnglandFemaleHumansPandemicsRetrospective Studiescervical cancerchemotherapydiagnosisgynaecological cancerpalliative careradiation therapysurgery

Identifiers

PMID35015334
PMCPMC9303941

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.