Evidence map›Paper›PMID 35015287›Full record

ArticleHormones (Athens, Greece)2022

Association of Prudent, Western, and Alternate Healthy Eating Index (AHEI-2010) dietary patterns with serum testosterone and sex hormone binding globulin levels in men.

David S Lopez, Lydia Liu, Stephanie A Smith-Warner, Konstantinos K Tsilidis, Carrie Daniel, Jacques Baillargeon, Sabine Rohrmann, Elizabeth A Platz, Edward Giovannucci

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Hormones (Athens, Greece), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 8 institutions in 5 countries.

David S LopezDeparment of Preventive Medicine and Population Health, University of Texas Medical Branch, Galveston, TX, USA. davlopez@utmb.edu.ORCID http://orcid.org/0000-0002-2321-0372
Lydia LiuDepartments of Nutrition and Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Stephanie A Smith-WarnerDepartments of Nutrition and Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Konstantinos K TsilidisDepartment of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK.
Carrie DanielDepartment of Epidemiology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
Jacques BaillargeonDeparment of Preventive Medicine and Population Health, University of Texas Medical Branch, Galveston, TX, USA.
Sabine RohrmannDepartment of Chronic Disease Epidemiology, Epidemiology, Biostatistics and Prevention Institute (EBPI), University of Zurich, Zurich, Switzerland.
Elizabeth A PlatzDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Edward GiovannucciDepartments of Nutrition and Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Harvard University · USBrigham and Women's Hospital · USJohns Hopkins University · USThe University of Texas MD Anderson Cancer Center · USThe University of Texas Medical Branch at Galveston · USUniversity of Ioannina · GRUniversity of the Gambia · GMUniversity of Zurich · CH

Funding

Dietary Etiology of Heart DiseaseR01HL035464 · NHLBI · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI ERIC B RIMM, Qi Sun · 1986 to 2026
$13.6M
Cancer Epidemiology Cohort in Male Health ProfessionalsUM1CA167552 · NCI · HARVARD SCHOOL OF PUBLIC HEALTH · PI WILLETT, WALTER C. · 2012 to 2016
$11.5M
The Texas Resource Center on Minority Aging Research (RCMAR)P30AG059301 · NIA · UNIVERSITY OF TEXAS MED BR GALVESTON · PI Kyriakos S Markides, Fernando Riosmena · 2018 to 2026
$5.2M
NONPARAMETRIC ANALYSIS OF CENSORED DATAR01CA035464 · NCI · UNIVERSITY OF WISCONSIN MADISON · PI TANNER, MARTIN A · 1986 to 2000
$103k
NCI NIH HHS R01 HL35464NCI NIH HHS UM1 CA167552NHLBI NIH HHS R01 HL035464NIA NIH HHS P30 AG059301NIMHD NIH HHS L60 MD002942
6 · The paper itself

Abstract

purposeThe association of dietary patterns with testosterone (T) and sex hormone binding globulin (SHBG) levels remains unclear. We investigated the associations of dietary patterns with T and SHBG levels to determine whether these associations vary by obesity status.

methodsA cross-sectional analysis was conducted in 1376 middle-aged (≥ 40 years old) men of the Health Professionals Follow-up Study. Prudent (rich in whole grains and dietary fiber) and Western (rich in red meat and refined grains) diet scores were identified using principal component analysis. The Alternate Healthy Eating Index 2010 (AHEI-2010) score, a measure of overall diet quality, was defined based on foods and nutrients predictive of chronic disease risk.

resultsWe identified a weak inverse association between AHEI-2010 and T levels (P

conclusionWe observed a weak inverse association between AHEI-2010 and T levels. Null associations were identified for SHBG. Obesity status seemed to modulate associations of T and SHBG levels with diet scores, especially the AHEI-2010 and prudent diets. However, this research question warrants further investigation in prospective studies.

Indexed as

Diet, HealthySex Hormone-Binding GlobulinAdultCross-Sectional StudiesDietFollow-Up StudiesHumansMaleMiddle AgedProspective StudiesTestosteroneSex Hormone-Binding GlobulinTestosteroneDietary patternMenSHBGTestosterone

Identifiers

PMID35015287
PMCPMC9134265
OpenAlexW4206807423

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.