Evidence map›Paper›PMID 35015242›Full record

ArticleProbiotics and antimicrobial proteins2023

Effects of Antimicrobial Peptides Gal-13 on the Growth Performance, Intestinal Microbiota, Digestive Enzyme Activities, Intestinal Morphology, Antioxidative Activities, and Immunity of Broilers.

Yufei Wang, Jianzhen Li, Xixi Dai, Zhenhua Wang, Xueqin Ni, Dong Zeng, Yan Zeng, Dongmei Zhang, Kangcheng Pan

Abstract read
PubMed Publisher
In one paragraph

Article in Probiotics and antimicrobial proteins, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 32 citations in OpenAlex.

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  3. Review
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  9. Article
  10. Review
  11. Effects of dietaryFrontiers in microbiology · 2025
    Article
  12. Article
  13. Oral supplementation withFrontiers in veterinary science · 2025
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Surface Display ofFrontiers in immunology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Yufei Wang *College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, 611130, China.
Jianzhen Li *Chengdu Agricultural College, Chengdu, 611130, China.
Xixi Dai *Chongqing Three Gorges Vocational College, Chongqing, 404155, China.
Zhenhua WangChengdu Agricultural College, Chengdu, 611130, China.
Xueqin NiCollege of Veterinary Medicine, Sichuan Agricultural University, Chengdu, 611130, China.
Dong ZengCollege of Veterinary Medicine, Sichuan Agricultural University, Chengdu, 611130, China.
Yan ZengCollege of Veterinary Medicine, Sichuan Agricultural University, Chengdu, 611130, China.
Dongmei ZhangCollege of Veterinary Medicine, Sichuan Agricultural University, Chengdu, 611130, China.
Kangcheng PanCollege of Veterinary Medicine, Sichuan Agricultural University, Chengdu, 611130, China. pankangcheng71@126.com.ORCID 0000-0002-8898-933X
Sichuan Agricultural University · CNChongqing Three Gorges University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To evaluate the application effect of antimicrobial peptides Gal-13 (AMP Gal-13) instead of antibiotic feed additives, 90 7-day-old Ross 308 broilers were randomly divided into 3 groups. Group A was fed a basic diet as the control, and Groups B and C were supplemented with AMP Gal-13 (100 mg/kg and 200 mg/kg, respectively). After a 35-day feeding experiment, the weight and average daily gain (ADG) of the broilers in Group B were significantly higher than those of the broilers in Group A. The Enterococcus sp. and Escherichia coli counts in the ileum and cecum in Group A were significantly higher than those in Groups B and C, while the Lactic acid bacteria (LAB) and Bifidobacterium sp. counts were significantly lower. The amylase activity of the jejunum in Group B was significantly higher than that in Group A. The villus length (VL): crypt depth (CD) ratios of the jejunum and ileum in Group B were significantly higher than those in Group A. The glutathione peroxidase (GSH-Px) activities in the liver and serum in Groups B and C were significantly higher than those in Group A, while the malondialdehyde (MDA) activity was significantly lower. The titers of Newcastle disease virus (NDV)-specific antibodies were elevated significantly in Group B at the age of 42 days. Additionally, the weights of the spleen and thymus were significantly increased. The expression levels of Il-2, Il-6, Tgf-β4, Tnf-α, and Mif in the spleen in Groups B and C were significantly downregulated to different degrees; Il-4 expression in Group B was significantly upregulated, while Ifn-γ expression in Group C was significantly upregulated. The results suggested that adding AMP Gal-13 to the diet could improve intestinal digestion, the antioxidant capacity, and immune function, ultimately promoting the growth of broilers.

Indexed as

AntioxidantsGastrointestinal MicrobiomeAnimal FeedAnimalsAntimicrobial PeptidesChickensDietDietary SupplementsIntestinesAntimicrobial PeptidesAntioxidantsAntimicrobial peptidesAntioxidantBroilerGal-13ImmunoregulationIntestinal flora

Identifiers

PMID35015242
OpenAlexW4206254052

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.