Evidence map›Paper›PMID 35015191›Full record

ReviewHead and neck pathology2022

Metastatic HPV-Mediated Adenocarcinoma Arising from a Base of Tongue Primary: A Case Report with Cytomorphology and Molecular Findings with Review of the Literature.

Stephanie Zheng, Kelly R Magliocca, Michelle D Reid, Azeem S Kaka, Daniel Lubin

Open access · greenAbstract readCase ReportsReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Head and neck pathology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Stephanie ZhengDepartment of Pathology, Emory University Hospital Midtown, 550 Peachtree Street NE, Atlanta, GA, 30308, USA.
Kelly R MaglioccaDepartment of Pathology, Emory University Hospital Midtown, 550 Peachtree Street NE, Atlanta, GA, 30308, USA.
Michelle D ReidDepartment of Pathology, Emory University Hospital Midtown, 550 Peachtree Street NE, Atlanta, GA, 30308, USA.
Azeem S KakaDepartment of Otolaryngology, Head and Neck Surgery, Emory University Hospital Midtown, 550 Peachtree Street NE, Atlanta, GA, 30308, USA.
Daniel LubinDepartment of Pathology, Emory University Hospital Midtown, 550 Peachtree Street NE, Atlanta, GA, 30308, USA. Daniel.Lubin@EmoryHealthcare.org.ORCID http://orcid.org/0000-0002-0409-2374
Emory University Hospital Midtown · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human papillomavirus (HPV)-mediated squamous cell carcinomas of the oropharynx are common, however only rare cases of HPV-mediated oropharyngeal adenocarcinoma have been reported to date. In this report, we describe a 50 year old nonsmoking male who originally presented with an enlarging neck mass. Fine needle aspiration cytology confirmed an HPV-mediated adenocarcinoma. Subsequent surgery identified a 0.7 cm base of tongue primary HPV-mediated carcinoma with focal glandular differentiation and a 4.0 cm cystic lymph node metastasis demonstrating entirely glandular differentiation. Next generation sequencing of the metastasis detected a pathogenic NOTCH1 mutation.

Indexed as

AdenocarcinomaAlphapapillomavirusHead and Neck NeoplasmsOropharyngeal NeoplasmsPapillomavirus InfectionsTongue NeoplasmsHumansMaleMiddle AgedPapillomaviridaeTongueBase of tongueCarcinomaHPV-mediated adenocarcinomaHuman papillomavirusNOTCH1Oropharynx

Identifiers

PMID35015191
PMCPMC9424432
OpenAlexW4205422264

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.