ArticleOrganic & biomolecular chemistry2022
Enantioselective organocatalytic syntheses of α-selenated α- and β-amino acid derivatives.
Article in Organic & biomolecular chemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Electrocatalytic Polarity Inversion of Azlactones: Access to α-Quaternary Amino Acids with Electron-Rich SOMOphiles.Angewandte Chemie (International ed. in English) · 2026Article
- Selenium-catalyzed organic transformations.iScience · 2026Review
- Article
- Towards an asymmetric β-selective addition of azlactones to allenoates.Beilstein journal of organic chemistry · 2024Article
- Enantioselective β-Selective Addition of Isoxazolidin-5-ones to Allenoates Catalyzed by Quaternary Ammonium Salts.Synthesis · 2023Article
- Stereoselective Syntheses of Masked β-Amino Acid Containing Phthalides.Helvetica chimica acta · 2022Article
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Authors and funding
5 authors.
Funding
Abstract
Selenium-containing amino acids are valuable targets but methods for the stereoselective α-selenation of simple amino acid precursors are rare. We herein report the enantioselective electrophilic α-selenation of azlactones (masked α-amino acid derivatives) and isoxazolidin-5-ones (masked β-amino acids) using Cinchona alkaloids as easily accessible organocatalysts. A variety of differently substituted derivatives was accessed with reasonable levels of enantioselectivities and further studies concerning the stability and suitability of these compounds for further manipulations have been carried out as well.
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