Evidence map›Paper›PMID 35014889›Full record

ArticleJournal of child neurology2022

Pediatric Autoimmune Encephalitis Following COVID-19 Infection.

Mark Hilado, Michelle Banh, James Homans, Arthur Partikian

Open access · greenAbstract read
In one paragraph

Article in Journal of child neurology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Coronavirus Infection in Neonates: Neurodevelopmental Outcomes at 18 Months of Age.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2023
    Article
  5. Review
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Mark HiladoPediatrics, 23336Los Angeles County+USC Medical CenterLos Angeles, CA, USA.ORCID 0000-0001-8065-508X
Michelle BanhInternal Medicine and Pediatrics, 23336Los Angeles County+USC Medical Center, Los Angeles, CA, USA.ORCID 0000-0003-1411-1919
James HomansPediatric Infectious Diseases, 23336Los Angeles County+USC Medical Center, Los Angeles, CA, USA.ORCID 0000-0003-0708-166X
Arthur PartikianPediatric Neurology, 23336Los Angeles County+USC Medical Center, Los Angeles, CA, USA.
LAC+USC Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Similar to the pathogenesis of autoimmune disease, SARS-CoV-2 (COVID-19) infection has been shown to be associated with dysregulated and persistent inflammatory reactions and production of some antibodies. We report 3 pediatric patients found to have serum SARS-CoV-2 antibodies who presented with neurologic findings suggestive of postinfectious autoimmune-mediated encephalitis. All 3 cases showed lymphocytic pleocytosis on cerebrospinal fluid studies and marked improvement in neurologic symptoms after high-dose intravenous corticosteroids. The manifestations of SARS-CoV-2 infection in the pediatric population are still an evolving area of study, and these cases suggest autoimmune-mediated encephalitis as yet another SARS-CoV-2 related complication.

Indexed as

COVID-19EncephalitisHashimoto DiseaseChildHumansSARS-CoV-2COVID-19, autoimmune, encephalitis, pediatrics, postinfectious

Identifiers

PMID35014889
PMCPMC9066234
OpenAlexW4205370971

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.