Evidence map›Paper›PMID 35014888›Full record

Observational studyJournal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners2023

Impact of the COVID-19 pandemic on new starts to oral oncology medications in the US.

Lynn Neilson, Monal Kohli, Kiraat D Munshi, Samuel K Peasah, Rochelle Henderson, Vida Passero, Chester B Good

Open access · greenAbstract readObservational Study
In one paragraph

Observational study in Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Lynn NeilsonCenters for High Value Health Care and Value Based Pharmacy Initiatives, 82584UPMC Health Plan Insurance Services Division, Pittsburgh, PA, USA.
Monal KohliEvernorth, St Louis, MO, USA.
Kiraat D MunshiEvernorth, St Louis, MO, USA.
Samuel K PeasahCenters for High Value Health Care and Value Based Pharmacy Initiatives, 82584UPMC Health Plan Insurance Services Division, Pittsburgh, PA, USA.
Rochelle HendersonEvernorth, St Louis, MO, USA.
Vida Passero367567VA Pittsburgh Healthcare System, Pittsburgh, PA, USA.
Chester B GoodCenters for High Value Health Care and Value Based Pharmacy Initiatives, 82584UPMC Health Plan Insurance Services Division, Pittsburgh, PA, USA.ORCID 0000-0003-4388-4558
University of Pittsburgh · USUPMC Center for High Value Health Care · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe COVID-19 pandemic has had a significant impact on healthcare delivery. Although others have documented the impact on new cancer diagnoses, trends in new starts for oncology drugs are less clear. We examined changes in new users of oral oncology medications in the US following COVID-19 stay-at-home orders in 2020 compared to prior years.

methodsWe examined prescription data for members enrolled with a national pharmacy benefits manager in the US from January 1-October 31 of 2018, 2019, and/or 2020. This is a retrospective, observational study comparing new users per 100,000 members per month for all oral oncology drugs, and separately for breast, lung, and prostate cancer, leukemia, and melanoma oral drugs. We performed a difference-in-differences analysis for change in new users from pre-period (prior to pandemic-induced disruption, January-March), to post-period (following pandemic-induced disruption, April-October), between 2020 and 2019, and 2020 and 2018.

resultsNew oral oncology drug users per 100,000 members per month declined by an additional 11.3% in the 2020 post-period compared to 2019 (

conclusionsLong-term implications of delays in cancer treatment initiation are unclear, although there is concern that patient outcomes may be negatively impacted.

Indexed as

COVID-19LeukemiaMelanomaProstatic NeoplasmsHumansMalePandemicsPharmaceutical PreparationsPharmaceutical PreparationscancerCoronavirusCOVID-19oral oncology medicationstherapeutics

Identifiers

PMID35014888
PMCPMC9902798
OpenAlexW4206181728

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.