ArticleJournal of the American Heart Association2022
Trends in the Incidence of New-Onset Hypertensive Disorders of Pregnancy Among Rural and Urban Areas in the United States, 2007 to 2019.
Article in Journal of the American Heart Association, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 80 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
80 citing papers in PubMed, 2 syntheses or guidelines pooled it, 112 citations in OpenAlex.
- Integrating Social and Clinical Determinants of Pre-Eclampsia: A Hierarchical Systematic Review and Conceptual Framework for Prevention.BJOG : an international journal of obstetrics and gynaecology · 2026Pooled it
- Long-term cardiovascular outcome in women with preeclampsia in Korea: a large population-based cohort study and meta-analysis.Scientific reports · 2024Pooled it
- The sedentary behavior reduction in pregnancy intervention (SPRING) pilot and feasibility randomized trial.BMC pregnancy and childbirth · 2024Trial
- Decoding systemic vascular health and hypertensive disorders in pregnancy through retinal imaging and Visionary AI.Nature biotechnology · 2026Article
- Budget Impact Model of a Novel cfRNA Test-and-Treat Strategy for Preeclampsia in Advanced Maternal Age Pregnancies Compared with Current Guidelines.PharmacoEconomics - open · 2026Article
- Hypertensive disorders of pregnancy and women's health throughout the life course: an update review 2025-2026.Hypertension research : official journal of the Japanese Society of Hypertension · 2026Review
- Obstetric History Versus Biomarkers: Hypertension Risk Up to 15 Years Postpartum.Hypertension (Dallas, Tex. : 1979) · 2026Article
- Sleep and Cardiovascular Health Among Women With a History of Hypertensive Disorders of Pregnancy: Pilot Observational Study.JMIR cardio · 2026Observational
- Food desert residence and prenatal diet quality.Pregnancy (Hoboken, N.J.) · 2026Article
- Pregestational Cardiometabolic Biomarkers and Future Hypertensive Disorders of Pregnancy.JAMA network open · 2026Article
- Association Between Changes in Maternal Age Distribution and Hypertensive Disorders of Pregnancy in the United States, 2011-2021.Circulation. Population health and outcomes · 2026Article
- COVID-19 vaccination during or just prior to pregnancy and hypertensive disorders of pregnancy.Vaccine · 2026Article
- Exploring Maternal Mental Health Conditions and Urban-Rural Disparities in Hypertensive Disorders of Pregnancy in South Carolina: A Fairlie Decomposition Approach.Maternal and child health journal · 2026Article
- Rising Burden of Hypertensive Heart Disease Mortality Among Young Adults in the United States, 1999 to 2024.The American journal of cardiology · 2026Article
- Adverse Materno-Foetal Outcomes of Pre-Eclampsia at a Rural Tertiary Hospital in the Eastern Cape Province of South Africa.International journal of environmental research and public health · 2025Article
- Pre-pregnancy and gestational cardiometabolic disorders and risk of preterm birth and infant mortality.Journal of global health · 2025Article
- A scoping review comparing individual and multi-level physical activity interventions in rural women in the United States.BMC public health · 2025Article
- Heterogeneity in Prepregnancy Hypertension Among Hispanic Origin Groups.Journal of the American Heart Association · 2025Article
- Localization and quantification of placentalPhysiological genomics · 2025Article
- Bending the Curve in Maternal Mortality: Pregnancy as a Moment for Cardiovascular Disease Prevention.Circulation · 2025Article
20 more citing papers are in PubMed but not listed here.
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
Background Hypertensive disorders of pregnancy are growing public health problems that contribute to maternal morbidity, mortality, and future risk of cardiovascular disease. Given established rural-urban differences in maternal cardiovascular health, we described contemporary trends in new-onset hypertensive disorders of pregnancy in the United States. Methods and Results We conducted a serial, cross-sectional analysis of 51 685 525 live births to individuals aged 15 to 44 years from 2007 to 2019 using the Centers for Disease Control and Prevention Natality Database. We included gestational hypertension and preeclampsia/eclampsia in individuals without chronic hypertension and calculated the age-adjusted incidence (95% CI) per 1000 live births overall and by urbanization status (rural or urban). We used Joinpoint software to identify inflection points and calculate rate of change. We quantified rate ratios to compare the relative incidence in rural compared with urban areas. Incidence (95% CI) of new-onset hypertensive disorders of pregnancy increased from 2007 to 2019 in both rural (48.6 [48.0-49.2] to 83.9 [83.1-84.7]) and urban (37.0 [36.8-37.2] to 77.2 [76.8-77.6]) areas. The rate of annual increase in new-onset hypertensive disorders of pregnancy was more rapid after 2014 with greater acceleration in urban compared with rural areas. Rate ratios (95% CI) comparing incidence of new-onset hypertensive disorders of pregnancy in rural and urban areas decreased from 1.31 (1.30-1.33) in 2007 to 1.09 (1.08-1.10) in 2019. Conclusions Incidence of new-onset hypertensive disorders of pregnancy doubled from 2007 to 2019 with persistent rural-urban differences highlighting the need for targeted interventions to improve the health of pregnant individuals and their offspring.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.