SynthesisJournal of the American Heart Association2022
Breastfeeding Is Associated With a Reduced Maternal Cardiovascular Risk: Systematic Review and Meta-Analysis Involving Data From 8 Studies and 1 192 700 Parous Women.
Synthesis in Journal of the American Heart Association, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 107 papers, 8 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
107 citing papers in PubMed, 8 syntheses or guidelines pooled it.
- A systematic review of breastfeeding prevalence, duration and determining factors in women with type 1 and type 2 diabetes mellitus.Diabetic medicine : a journal of the British Diabetic Association · 2026Pooled it
- Family-Centred Breastfeeding Interventions to Improve Exclusive Breastfeeding: A Systematic Review and Meta-Analysis.Nursing open · 2026Pooled it
- Associations of breastfeeding with maternal and child health outcomes: umbrella review.The American journal of clinical nutrition · 2025Pooled it
- Self-Care Interventions for Preventing Cardiovascular Diseases After Hypertensive Pregnancy Disorders: A Systematic Review and Meta-Analysis.BJOG : an international journal of obstetrics and gynaecology · 2025Pooled it
- Human Milk Feeding in Inherited Metabolic Disorders: A Systematic Review of Growth, Metabolic Control, and Neurodevelopment Outcomes.Journal of inherited metabolic disease · 2025Pooled it
- Guidelines for assessing maternal cardiovascular physiology during pregnancy and postpartum.American journal of physiology. Heart and circulatory physiology · 2024Guideline
- Support for healthy breastfeeding mothers with healthy term babies.The Cochrane database of systematic reviews · 2022Pooled it
- Risk factors for self-reported insufficient milk during the first 6 months of life: A systematic review.Maternal & child nutrition · 2022Pooled it
- Overcoming Barriers to Exclusive Breastfeeding in Lao PDR: Social Transfer Intervention Randomised Controlled Trial.Nutrients · 2025Trial
- Efficacy of an mHealth-delivered behavioral intervention on weight loss and cardiometabolic risk in African American postpartum people with overweight or obesity: the SnapBack randomized controlled trial.Obesity (Silver Spring, Md.) · 2024Trial
- Trial
- Breastfeeding initiation and duration among people with mild chronic hypertension: a secondary analysis of the Chronic Hypertension and Pregnancy trial.American journal of obstetrics & gynecology MFM · 2023Trial
- Cardiovascular health and depression among postpartum women in the United States.American journal of preventive cardiology · 2026Article
- Examining Relationships Between Multiple Adverse Social Determinants of Health, Maternal Depressive Symptoms, Timing of Solid Food Introduction, and Breastfeeding Duration Among Black or African American Women.Breastfeeding medicine : the official journal of the Academy of Breastfeeding Medicine · 2026Article
- Combined hormonal versus nonhormonal versus progestin-only contraceptives for postpartum contraception in lactating individuals.The Cochrane database of systematic reviews · 2026Article
- Association Between Hypertensive Disorders of Pregnancy, Lifestyle Factors, and Premature Cardiovascular Events.JACC. Advances · 2026Article
- Prolactin in high-metabolic risk pregnancies: Associations with maternal obesity and metabolic health.Acta obstetricia et gynecologica Scandinavica · 2026Observational
- The impact of one-to-one peer support on mothers' personal breastfeeding goals and emotional well-being: a scoping review.Public health nutrition · 2026Article
- Paid family leave to promote breastfeeding: catching policy up to the science.Pediatric research · 2026Review
- Perinatal depression and breastfeeding: a longitudinal investigation of the bidirectional relationship in Pakistan.Archives of women's mental health · 2026Article
47 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background Breastfeeding has been robustly linked to reduced maternal risk of breast cancer, ovarian cancer, and type 2 diabetes. We herein systematically reviewed the published evidence on the association of breastfeeding with maternal risk of cardiovascular disease (CVD) outcomes. Methods and Results Our systematic search of PubMed and Web of Science of articles published up to April 16, 2021, identified 8 relevant prospective studies involving 1 192 700 parous women (weighted mean age: 51.3 years at study entry, 24.6 years at first birth; weighted mean number of births: 2.3). A total of 982 566 women (82%) reported having ever breastfed (weighted mean lifetime duration of breastfeeding: 15.6 months). During a weighted median follow-up of 10.3 years, 54 226 CVD, 26 913 coronary heart disease, 30 843 stroke, and 10 766 fatal CVD events were recorded. In a random-effects meta-analysis, the pooled multivariable-adjusted hazard ratios comparing parous women who ever breastfed to those who never breastfed were 0.89 for CVD (95% CI, 0.83-0.95; I
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.