ArticleACS applied bio materials2022
Water-Soluble Luminescent Silicon Nanocrystals by Plasma-Induced Acrylic Acid Grafting and PEGylation.
Article in ACS applied bio materials, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed, 8 citations in OpenAlex.
- Plasma-Assisted and Green Routes to Silicon and Carbon Quantum Dots: A Critical Comparison of Synthesis-Structure-Property Relationships.Nanomaterials (Basel, Switzerland) · 2026Review
- Effect of the surface coverage of an alkyl carboxylic acid monolayer on waterborne and cellular uptake behaviors for silicon quantum dots.Scientific reports · 2022Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
Luminescent silicon nanocrystals are promising nanomaterials for biomedical applications due to their unique optical properties and biocompatibility. Here, we demonstrate a two-step surface modification approach coupling gas-phase and liquid-phase methods to synthesize PEGylated acrylic acid grafted silicon nanocrystals with near-infrared emission in water and biological media. First, acrylic acid grafted silicon nanocrystals are synthesized by an all-gas-phase approach on a millisecond time scale, omitting high temperature and postpurification processes. Subsequently, room-temperature PEGylation is carried out with these acrylic acid grafted silicon nanocrystals, yielding stable colloidal dispersions in both water and high ionic strength Tyrode's buffer with 20-30 nm hydrodynamic diameters. The PEGylated silicon nanocrystals exhibit photoluminescence in the 650-900 nm near-IR window with quantum yields of ∼30% and ∼13% in deionized water and Tyrode's buffer, respectively, after a 7-day oxidation in water. The surface-functionalized Si NCs exhibit relatively small toxicity to MDA-MB-231 cells at concentrations relevant to bioimaging applications.
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