ArticleAdvanced materials (Deerfield Beach, Fla.)2022
Stretchable Mesh Nanoelectronics for 3D Single-Cell Chronic Electrophysiology from Developing Brain Organoids.
Article in Advanced materials (Deerfield Beach, Fla.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 71 papers, 1 of them a synthesis that pooled it.
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Who cites it
71 citing papers in PubMed, 1 synthesis or guideline pooled it, 144 citations in OpenAlex.
- Mapping the Cerebral Organoid Landscape: A Systematic Review of Preclinical 3D Models in Neuroscience.Advanced healthcare materials · 2026Pooled it
- Enabling Scalable Nanoscale 3D Printing via Laser-Driven Termination.Small (Weinheim an der Bergstrasse, Germany) · 2026Article
- Bringing cellular clarity to the cortical component of ALS with a high-density multi-electrode array system.The FEBS journal · 2026Review
- Three-dimensional microelectrode arrays forBiomedical engineering letters · 2026Review
- Neural dynamics of temporal interference stimulation monitoring by soft liquid metal interfaces across neural systems.Nature communications · 2026Article
- In situ graphene-seq: spatial transcriptomics and chronic electrophysiological characterization of tissue microenvironments.Nature communications · 2026Article
- Next-Generation Strategies for Neural Repair and Regeneration: Neural Organoid Transplantation in the CNS.Cell proliferation · 2026Review
- Microelectrode Arrays Technology for Brain-on-a-Chip Applications.Biosensors · 2026Review
- Bridging the Gap: Integrated High-Density Microelectrode Arrays for Cellular, Organoid, and Clinical Electrophysiology.Micromachines · 2026Review
- Organoid Brain-Machine-Interface Devices for Central Nervous System Repair.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Review
- Smart Nanotechnologies for Multimodal Neuromodulation and Brain Interfacing.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Review
- Integrating living biomaterials into neuroelectronic systems.Biomedical engineering letters · 2026Review
- Shape-conformal porous frameworks for full coverage of neural organoids and high-resolution electrophysiology.Nature biomedical engineering · 2026Article
- Growth-adaptive spring electronics for long-term, same-neuron mapping in the developing rat brain.bioRxiv : the preprint server for biology · 2026Article
- Toward continuous monitoring systems: emerging trends of on-chip sensors in organ-on-a-chip.Microsystems & nanoengineering · 2026Review
- Biotechnical Multiscale Engineering of Scaffolds for Stem Cell and Organoid Research.Small (Weinheim an der Bergstrasse, Germany) · 2026Review
- Multi-Channel Neural Interface for Neural Recording and Neuromodulation.Small methods · 2026Review
- Dynamically autofocused 3D pulsed laser micromachining enables advanced 3D bioelectronics.Science advances · 2025Article
- Inner ear organoids: Recent progress and potential applications.Fundamental research · 2025Review
- Neural vs Neuromorphic Interfaces: Where Are We Standing?Chemical reviews · 2025Review
11 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
Abstract
Human induced pluripotent stem cell derived brain organoids have shown great potential for studies of human brain development and neurological disorders. However, quantifying the evolution of the electrical properties of brain organoids during development is currently limited by the measurement techniques, which cannot provide long-term stable 3D bioelectrical interfaces with developing brain organoids. Here, a cyborg brain organoid platform is reported, in which "tissue-like" stretchable mesh nanoelectronics are designed to match the mechanical properties of brain organoids and to be folded by the organogenetic process of progenitor or stem cells, distributing stretchable electrode arrays across the 3D organoids. The tissue-wide integrated stretchable electrode arrays show no interruption to brain organoid development, adapt to the volume and morphological changes during brain organoid organogenesis, and provide long-term stable electrical contacts with neurons within brain organoids during development. The seamless and noninvasive coupling of electrodes to neurons enables long-term stable, continuous recording and captures the emergence of single-cell action potentials from early-stage brain organoid development.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.