Evidence map›Paper›PMID 35014682›Full record

ArticleOncology reports2022

10Z‑Hymenialdisine inhibits angiogenesis by suppressing NF‑κB activation in pancreatic cancer cell lines.

Goro Ueda, Yoichi Matsuo, Hiromichi Murase, Yoshinaga Aoyama, Tomokatsu Kato, Kan Omi, Yuichi Hayashi, Hiroyuki Imafuji, Kenta Saito, Ken Tsuboi and 6 more

Open access · hybridAbstract read
In one paragraph

Article in Oncology reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Article
  3. Bioactive potency of extracts fromBiomedical reports · 2025
    Article
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  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 2 institutions in 1 country.

Goro UedaDepartment of Gastroenterological Surgery, Nagoya City University Graduate School of Medical Sciences and Medical School, Mizuho‑cho, Mizuho‑ku, Nagoya, Aichi 467-8601, Japan.
Yoichi MatsuoDepartment of Gastroenterological Surgery, Nagoya City University Graduate School of Medical Sciences and Medical School, Mizuho‑cho, Mizuho‑ku, Nagoya, Aichi 467-8601, Japan.
Hiromichi MuraseDepartment of Gastroenterological Surgery, Nagoya City University Graduate School of Medical Sciences and Medical School, Mizuho‑cho, Mizuho‑ku, Nagoya, Aichi 467-8601, Japan.
Yoshinaga AoyamaDepartment of Gastroenterological Surgery, Nagoya City University Graduate School of Medical Sciences and Medical School, Mizuho‑cho, Mizuho‑ku, Nagoya, Aichi 467-8601, Japan.
Tomokatsu KatoDepartment of Gastroenterological Surgery, Nagoya City University Graduate School of Medical Sciences and Medical School, Mizuho‑cho, Mizuho‑ku, Nagoya, Aichi 467-8601, Japan.
Kan OmiDepartment of Gastroenterological Surgery, Nagoya City University Graduate School of Medical Sciences and Medical School, Mizuho‑cho, Mizuho‑ku, Nagoya, Aichi 467-8601, Japan.
Yuichi HayashiDepartment of Gastroenterological Surgery, Nagoya City University Graduate School of Medical Sciences and Medical School, Mizuho‑cho, Mizuho‑ku, Nagoya, Aichi 467-8601, Japan.
Hiroyuki ImafujiDepartment of Gastroenterological Surgery, Nagoya City University Graduate School of Medical Sciences and Medical School, Mizuho‑cho, Mizuho‑ku, Nagoya, Aichi 467-8601, Japan.
Kenta SaitoDepartment of Gastroenterological Surgery, Nagoya City University Graduate School of Medical Sciences and Medical School, Mizuho‑cho, Mizuho‑ku, Nagoya, Aichi 467-8601, Japan.
Ken TsuboiDepartment of Gastroenterological Surgery, Nagoya City University Graduate School of Medical Sciences and Medical School, Mizuho‑cho, Mizuho‑ku, Nagoya, Aichi 467-8601, Japan.
Mamoru MorimotoDepartment of Gastroenterological Surgery, Nagoya City University Graduate School of Medical Sciences and Medical School, Mizuho‑cho, Mizuho‑ku, Nagoya, Aichi 467-8601, Japan.
Ryo OgawaDepartment of Gastroenterological Surgery, Nagoya City University Graduate School of Medical Sciences and Medical School, Mizuho‑cho, Mizuho‑ku, Nagoya, Aichi 467-8601, Japan.
Hiroki TakahashiDepartment of Gastroenterological Surgery, Nagoya City University Graduate School of Medical Sciences and Medical School, Mizuho‑cho, Mizuho‑ku, Nagoya, Aichi 467-8601, Japan.
Akira MitsuiDepartment of Gastroenterological Surgery, Nagoya City University West Medical Center, Kita‑ku, Nagoya, Aichi 462-8508, Japan.
Masahiro KimuraDepartment of Gastrointestinal Surgery, Nagoya City East Medical Center, Chikusa‑ku, Nagoya, Aichi 464-8547, Japan.
Shuji TakiguchiDepartment of Gastroenterological Surgery, Nagoya City University Graduate School of Medical Sciences and Medical School, Mizuho‑cho, Mizuho‑ku, Nagoya, Aichi 467-8601, Japan.
Nagoya City University · JPNagoya Medical Center · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

10Z‑Hymenialdisine is a natural product derived from the marine sponge

Indexed as

Angiogenesis InhibitorsAnimalsAzepinesCell Line, TumorDisease Models, AnimalHumansMiceNeovascularization, PathologicNF-kappa BPancreatic NeoplasmsPyrrolesAngiogenesis InhibitorsAzepineshymenialdisineNF-kappa BPyrroles10Z‑Hymenialdisineangiogenesisnatural productNF‑κBpancreatic cancer

Identifiers

PMID35014682
PMCPMC8771196
OpenAlexW4206059312

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.