ArticleIndian pediatrics2022
Profile of Neurological Manifestations in Children Presenting with Rickettsial Disease.
Article in Indian pediatrics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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Who cites it
5 citing papers in PubMed, 10 citations in OpenAlex.
- Tick-induced neurological disorders.Journal of neurology · 2025Review
- Inflammatory markers in cerebrospinal fluid in pediatric Brazilian spotted fever with neurological manifestations.Revista do Instituto de Medicina Tropical de Sao Paulo · 2025Article
- Neurological manifestation of Brazilian spotted fever in childhood.Revista do Instituto de Medicina Tropical de Sao Paulo · 2024Article
- Article
- Advances in the Diagnosis and Treatment of Pediatric Arterial Ischemic Stroke.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2023Review
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo study the profile of neurological manifestation of rickettsial disease in children.
methodsReview of hospital records was done in a tertiary care hospital for the period from January to December, 2020. Data of all the children fulfilling the inclusion criteria i.e., clinical criteria and serology were retrieved from the hospital records.
resultsOf the total 7974 children admitted over this period, 178 were diagnosed with rickettsial disease wherein 54 (33.3%) had neurological involvement. Convulsions (59%), altered sensorium (56%), headache (44%), meningeal signs (37%), ataxia, (11%), lateral rectus palsy (7.5%) and stroke (7.5%) were the major neurological manifestations. Cerebrospinal fluid (CSF) analysis done in 30 (55%) children showed pleocytosis [median (IQR) cells 15 (3.75, 50)] with lymphocyte predominance [median (IQR) lymphocytes 11.5 (3, 38.75)] and elevated proteins [median IQR 41.5 (29.75,61)]. Neuroimaging abnormalities noticed were cerebral edema (n=7), cerebellar hyperintensities (n=5), basal ganglia infarcts (n=2) and hippocampal hyperintensities (n=1).
conclusionEarly recognition of rickettsial infection as a cause of neurological manifestation would facilitate early specific management.
Indexed as
Identifiers
35014614PMC8964390W4206866095What OpenQuestion holds
Registered trials
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