Evidence map›Paper›PMID 35014034›Full record

ReviewThe Journal of physiology2022

The LRRC family of BK channel regulatory subunits: potential roles in health and disease.

Vivian Gonzalez-Perez, Yu Zhou, Matthew A Ciorba, Christopher J Lingle

Open access · bronzeAbstract readReview
In one paragraph

Review in The Journal of physiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 26 citations in OpenAlex.

  1. Trial
  2. Potassium Channels of the Airway Epithelium.Acta physiologica (Oxford, England) · 2026
    Review
  3. Review
  4. Article
  5. Tuning the gate and the gear: The LRRC26 (γ1) subunit modulates intrinsic gating and voltage-sensor coupling of the BK channel.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  6. Article
  7. Paraoxonase 3 regulates the pore-forming α subunit of the large-conductance KBiochimica et biophysica acta. Molecular cell research · 2025
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Andrology · 2025
    Review
  13. Large conductance voltage-and calcium-activated KFrontiers in pharmacology · 2024
    Review
  14. Review
  15. Article
  16. Review
  17. CaInternational journal of molecular sciences · 2023
    Review
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Vivian Gonzalez-PerezDepartment of Anesthesiology, Washington University School of Medicine, St Louis, MO, USA.
Yu ZhouDepartment of Anesthesiology, Washington University School of Medicine, St Louis, MO, USA.ORCID 0000-0002-1407-6140
Matthew A CiorbaDepartment of Internal Medicine, Division of Gastroenterology, Washington University School of Medicine, St Louis, MO, USA.
Christopher J LingleDepartment of Anesthesiology, Washington University School of Medicine, St Louis, MO, USA.ORCID 0000-0002-9916-3795
Washington University in St. Louis · US

Funding

SLO family potassium channels: function and physiologyR35GM118114 · NIGMS · WASHINGTON UNIVERSITY · PI LINGLE, CHRISTOPHER J · 2016 to 2025
$6.9M
AUXILIARY SUBUNITS OF CA2+ ACTIVATED K+ CHANNELSR01GM081748 · NIGMS · WASHINGTON UNIVERSITY · PI LINGLE, CHRISTOPHER J · 2008 to 2015
$3.2M
NIGMS NIH HHS R01 GM081748NIGMS NIH HHS R35 GM118114
6 · The paper itself

Abstract

Large conductance K

Indexed as

Hair Cells, Auditory, InnerLarge-Conductance Calcium-Activated Potassium ChannelsAnimalsColonFemaleLarge-Conductance Calcium-Activated Potassium Channel alpha SubunitsMembrane ProteinsMiceMice, KnockoutProtein DomainsLarge-Conductance Calcium-Activated Potassium Channel alpha SubunitsLarge-Conductance Calcium-Activated Potassium ChannelsLRRC52 protein, mouseMembrane ProteinsBK channelsgoblet cellsintestinal epitheliumleucine-rich-repeat proteins (LRR protein)potassium ion channelsulcerative colitis

Identifiers

PMID35014034
PMCPMC8930516
OpenAlexW4205656428

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.