Evidence map›Paper›PMID 35014018›Full record

ArticleRevista de neurologia2022

[Preliminary study of the temporal variables of continuous speech in patients with neurodegenerative syndromes of the frontotemporal lobar degeneration spectrum].

L Baqué, M J Machuca, M A Santos-Santos

Open access · greenAbstract read
In one paragraph

Article in Revista de neurologia, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

L BaquéUniversitat Autònoma de Barcelona, Bellaterra (Cerdanyola del Vallés), España.
M J MachucaUniversitat Autònoma de Barcelona, Bellaterra (Cerdanyola del Vallés), España.
M A Santos-SantosHospital de la Santa Creu i Sant Pau / Sant Pau Biomedical Research Institute (IIb Sant Pau), Barcelona, España.
Universitat Autònoma de Barcelona · ESHospital de Sant Pau · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionNeurodegenerative diseases, especially frontotemporal lobar degeneration and Alzheimer's disease, often lead to impaired language functions, and so speech analysis can provide objective measures with which to classify the different syndromes.

aimTo study the nature, cognitive correlates and clinical utility of 21 variables related to speech and silence times. SUBJECTS AND

methodsDerivation of acoustic variables with Praat in three spontaneous speech tasks conducted in 22 subjects, distributed in six diagnostic groups (five with neurodegenerative diseases + control). A descriptive analysis is performed, with ROC and principal component curves, to study how acoustic variables are related to the different neurodegenerative syndromes and what information they can provide.

resultsThree groups of variables are identified related, respectively, to: a) total number of silent pauses and total duration of the task; b) variability of the phonic groups; and c) variability of the periods of silence. These components correlate differentially with the different syndromes studied.

conclusionsDetailed analysis of speech and silence times can provide relevant information for the diagnosis of different neurodegenerative syndromes that are not reflected in traditional neuropsychological assessments. Thus, the total number of silent pauses may be a valuable aid in discriminating patients with lexical access deficits, phonic group parameters seem to reflect motor speech problems, and pause variability is associated with dysexecutive and global impairment.

Indexed as

AgedAged, 80 and overFemaleFrontotemporal Lobar DegenerationHumansMaleNeurodegenerative DiseasesProspective StudiesSpeechSyndromeTime Factors

Identifiers

PMID35014018
PMCPMC11500026
OpenAlexW4205306594

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.