Evidence map›Paper›PMID 35013928›Full record

ArticleJournal of general internal medicine2022

The Heart and Cannabis (THC) Cohort: Differences in Baseline Health and Behaviors by Cannabis Use.

Salomeh Keyhani, Beth E Cohen, Marzieh Vali, Katherine J Hoggatt, Dawn M Bravata, Peter C Austin, Emily Lum, Deborah S Hasin, Carl Grunfeld, Michael G Shlipak

Open access · hybridAbstract read
In one paragraph

Article in Journal of general internal medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 3 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Salomeh KeyhaniDepartment of Medicine, University of California, San Francisco, San Francisco, CA, USA. Salomeh.Keyhani@ucsf.edu.ORCID 0000-0001-9124-9618
Beth E CohenDepartment of Medicine, University of California, San Francisco, San Francisco, CA, USA.
Marzieh ValiNorthern California Institute for Research and Education, San Francisco, CA, USA.
Katherine J HoggattDepartment of Medicine, University of California, San Francisco, San Francisco, CA, USA.
Dawn M BravataMedicine Service, Richard L. Roudebush VA Medical Center, Indianapolis, IN, USA.
Peter C AustinUniversity of Toronto, Toronto, Canada.
Emily LumNorthern California Institute for Research and Education, San Francisco, CA, USA.
Deborah S HasinMailman School of Public Health, Columbia University, New York, NY, USA.
Carl GrunfeldDepartment of Medicine, University of California, San Francisco, San Francisco, CA, USA.
Michael G ShlipakDepartment of Medicine, University of California, San Francisco, San Francisco, CA, USA.
San Francisco VA Medical Center · USNorthern California Institute for Research and Education · USColumbia University · USRichard L. Roudebush VA Medical Center · USUniversity of Toronto · CA

Funding

Impact of marijuana on adherence, risk factor control and cardiovascular eventsR01HL130484 · NHLBI · NORTHERN CALIFORNIA INSTITUTE/RES/EDU · PI KEYHANI, SALOMEH · 2017 to 2020
$2.9M
NHLBI NIH HHS R01 HL130484
6 · The paper itself

Abstract

backgroundEvidence on the cardiovascular health effects of cannabis use is limited. We designed a prospective cohort study of older Veterans (66 to 68 years) with coronary artery disease (CAD) to understand the cardiovascular consequences of cannabis use. We describe the cohort construction, baseline characteristics, and health behaviors that were associated with smoking cannabis.

objectiveTo understand the cardiovascular consequences of cannabis use.

designWe designed a prospective cohort study of older Veterans (66 to 68 years) with CAD.

participantsA total of 1,015 current cannabis smokers and 3,270 non-cannabis smokers with CAD. MAIN MEASURES: Using logistic regression, we examined the association of baseline variables with smoking cannabis in the past 30 days.

resultsThe current cannabis smokers and non-current smokers were predominantly male (97.2% vs 97.1%, p=0.96). Characteristics associated with recent cannabis use in multivariable analyses included lack of a high school education (odds ratio [OR] 2.15, 95% confidence interval [CI]: 1.10 to 4.19), financial difficulty (OR 1.47, 95% CI: 1.02 to 2.11), tobacco use (OR 3.02, 95% CI: 1.66 to 5.48), current drug use (OR 2.82, 95% CI: 1.06 to 7.46), and prior drug use (OR 2.84, 95% CI: 2.11 to 3.82). In contrast, compared to individuals with 0 to 1 comorbid conditions, those with 5 chronic conditions or more (OR 0.43, 95% CI: 0.27 to 0.70) were less likely to smoke cannabis.

conclusionsIn this older high-risk cohort, smoking cannabis was associated with higher social and behavioral risk, but with fewer chronic health conditions.

Indexed as

CannabisMarijuana SmokingCannabinoid Receptor AgonistsDronabinolFemaleHealth BehaviorHumansMaleProspective StudiesCannabinoid Receptor AgonistsDronabinolcannabiscohortcoronary artery diseaserisk factorssmoking

Identifiers

PMID35013928
PMCPMC9585109
OpenAlexW4206309773

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.