Evidence map›Paper›PMID 35013924›Full record

ReviewApplied biochemistry and biotechnology2022

Environmental Distribution, Metabolic Fate, and Degradation Mechanism of Chlorpyrifos: Recent and Future Perspectives.

Rahul S Bhende, Upasana Jhariya, Shweta Srivastava, Sakina Bombaywala, Sanchita Das, Nishant A Dafale

Abstract readReview
PubMed Publisher
In one paragraph

Review in Applied biochemistry and biotechnology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
3.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 66 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Microbiology and Biochemistry of Pesticides Biodegradation.International journal of molecular sciences · 2023
    Review
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Rahul S BhendeEnvironmental Biotechnology and Genomics Division, CSIR-National Environmental Engineering Research Institute (NEERI), Nagpur, 440020, India.
Upasana JhariyaEnvironmental Biotechnology and Genomics Division, CSIR-National Environmental Engineering Research Institute (NEERI), Nagpur, 440020, India.
Shweta SrivastavaEnvironmental Biotechnology and Genomics Division, CSIR-National Environmental Engineering Research Institute (NEERI), Nagpur, 440020, India.
Sakina BombaywalaEnvironmental Biotechnology and Genomics Division, CSIR-National Environmental Engineering Research Institute (NEERI), Nagpur, 440020, India.
Sanchita DasEnvironmental Biotechnology and Genomics Division, CSIR-National Environmental Engineering Research Institute (NEERI), Nagpur, 440020, India.
Nishant A DafaleEnvironmental Biotechnology and Genomics Division, CSIR-National Environmental Engineering Research Institute (NEERI), Nagpur, 440020, India. na_dafale@neeri.res.in.
National Environmental Engineering Research Institute · INAcademy of Scientific and Innovative Research · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pesticides play a significant role in crop production and have become an inevitable part of the modern environment due to their extensive distribution throughout the soil ecosystem. Prophylactic applications of chlorpyrifos (CP) affect soil fertility, modify soil microbial community structure, and pose potential health risks to the nontarget organisms. Bioremediation through microbial metabolism is found to be an ecofriendly and cheaper process for CP removal from the environment. So far, various bacterial and fungal communities have been reported for CP and its metabolites degradation. Organophosphorus hydrolase (OPH) and methyl parathion hydrolase (MPH) are crucial bacterial enzymes for CP degradation as they efficiently hydrolyze the unbreakable P-O and P = S bond. This review discusses the prospects of toxicity level, persistency, and harmful effects of CP on the environment. CP degradation mechanisms, metabolic pathways, and key enzymes, along with their structural details, are also featured. The highlights on molecular docking with OPH and MPH enzyme for CP show the best binding affinity with OPH; hence, it is an essential part of CP degradation. Simultaneously, metagenomic analysis of soil from contaminated agricultural lands and wastewater was analyzed with the goal to identify the dominant CP degraders and enzymes. The identification of potent degraders, key enzymes, and evaluation of microbial community dynamics upon pesticide exposure can be used as a warning for its dissemination and biomagnification into the food chain.

Indexed as

ChlorpyrifosPesticidesAryldialkylphosphataseBacteriaBiodegradation, EnvironmentalEcosystemHydrolasesMolecular Docking SimulationSoilAryldialkylphosphataseChlorpyrifosHydrolasesPesticidesSoilBioremediationChlorpyrifosDegradation pathwayMetagenomicsOrganophosphorus hydrolase

Identifiers

PMID35013924
OpenAlexW4206727469

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.