Evidence map›Paper›PMID 35013826›Full record

ArticleJournal of digital imaging2022

Unsupervised Deep Anomaly Detection for Medical Images Using an Improved Adversarial Autoencoder.

Haibo Zhang, Wenping Guo, Shiqing Zhang, Hongsheng Lu, Xiaoming Zhao

Open access · greenAbstract read
In one paragraph

Article in Journal of digital imaging, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
5.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 47 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Generative Inpainting-Based Anomaly Detection for CT Liver Tumor Detection.IEEE transactions on radiation and plasma medical sciences · 2025
    Article
  5. Article
  6. AI-Powered Mobile App for Nuclear Cataract Detection.Sensors (Basel, Switzerland) · 2025
    Article
  7. Article
  8. Review
  9. Review
  10. High-quality semi-supervised anomaly detection with generative adversarial networks.International journal of computer assisted radiology and surgery · 2024
    Article
  11. Review
  12. Article
  13. Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Haibo ZhangTaizhou Central Hospital (Taizhou University Hospital), Taizhou University, Zhejiang, 318000, China.
Wenping GuoTaizhou Central Hospital (Taizhou University Hospital), Taizhou University, Zhejiang, 318000, China.
Shiqing ZhangTaizhou Central Hospital (Taizhou University Hospital), Taizhou University, Zhejiang, 318000, China.
Hongsheng LuTaizhou Central Hospital (Taizhou University Hospital), Taizhou University, Zhejiang, 318000, China. luhs@tzc.edu.cn.
Xiaoming ZhaoTaizhou Central Hospital (Taizhou University Hospital), Taizhou University, Zhejiang, 318000, China. tzxyzxm@163.com.ORCID 0000-0002-4708-4171
Taizhou Central Hospital · CNHohai University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Anomaly detection has been applied in the various disease of medical practice, such as breast cancer, retinal, lung lesion, and skin disease. However, in real-world anomaly detection, there exist a large number of healthy samples, and but very few sick samples. To alleviate the problem of data imbalance in anomaly detection, this paper proposes an unsupervised learning method for deep anomaly detection based on an improved adversarial autoencoder, in which a module called chain of convolutional block (CCB) is employed instead of the conventional skip-connections used in adversarial autoencoder. Such CCB connections provide considerable advantages via direct connections, not only preserving both global and local information but also alleviating the problem of semantic disparity between the encoding features and the corresponding decoding features. The proposed method is thus able to capture the distribution of normal samples within both image space and latent vector space. By means of minimizing the reconstruction error within both spaces during training phase, higher reconstruction error during test phase is indicative of an anomaly. Our method is trained only on the healthy persons in order to learn the distribution of normal samples and can detect sick samples based on high deviation from the distribution of normality in an unsupervised way. Experimental results for multiple datasets from different fields demonstrate that the proposed method yields superior performance to state-of-the-art methods.

Indexed as

Diagnostic ImagingHumansAdversarial autoencodersChain of convolution blockDeep anomaly detectionMedical imagesUnsupervised

Identifiers

PMID35013826
PMCPMC8921374
OpenAlexW4205106353

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.