Evidence map›Paper›PMID 35013776›Full record

ArticleEuropean journal of nuclear medicine and molecular imaging2022

Preclinical evaluation of [

Tianyu Liu, Yue Wu, Linqing Shi, Liqiang Li, Biao Hu, Yanpu Wang, Hannan Gao, Xiaolu Yu, Xin Zhang, Huiyun Zhao and 3 more

Abstract read
PubMed Publisher
In one paragraph

Article in European journal of nuclear medicine and molecular imaging, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Development and Characterization of the [Molecular pharmaceutics · 2025
    Article
  7. Molecular Imaging of Cancer Stem Cells and Their Role in Therapy Resistance.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2025
    Review
  8. ImmunoPET imaging of EpCAM in solid tumours with nanobody tracers: a preclinical study.European journal of nuclear medicine and molecular imaging · 2025
    Article
  9. Review
  10. Review
  11. Immuno-PET of colorectal cancer with a CEA-targeted [68 Ga]Ga-nanobody: from bench to bedside.European journal of nuclear medicine and molecular imaging · 2023
    Article
  12. Review
  13. Review
  14. Review
  15. Single-Domain Antibody Theranostics on the Horizon.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2022
    Article
  16. Article
  17. Review
  18. RadioLabeling of the Mutant form of Anti-PlGF Nanobody byIranian journal of pharmaceutical research : IJPR
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Tianyu LiuMedical Isotopes Research Center, Department of Radiation Medicine, School of Basic Medical Sciences, Peking University, Beijing, 100191, People's Republic of China.
Yue WuMedical Isotopes Research Center, Department of Radiation Medicine, School of Basic Medical Sciences, Peking University, Beijing, 100191, People's Republic of China.
Linqing ShiMedical Isotopes Research Center, Department of Radiation Medicine, School of Basic Medical Sciences, Peking University, Beijing, 100191, People's Republic of China.
Liqiang LiMedical Isotopes Research Center, Department of Radiation Medicine, School of Basic Medical Sciences, Peking University, Beijing, 100191, People's Republic of China.
Biao HuMedical Isotopes Research Center, Department of Radiation Medicine, School of Basic Medical Sciences, Peking University, Beijing, 100191, People's Republic of China.
Yanpu WangMedical Isotopes Research Center, Department of Radiation Medicine, School of Basic Medical Sciences, Peking University, Beijing, 100191, People's Republic of China.
Hannan GaoMedical Isotopes Research Center, Department of Radiation Medicine, School of Basic Medical Sciences, Peking University, Beijing, 100191, People's Republic of China.
Xiaolu YuState Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, People's Republic of China.
Xin ZhangMedical Isotopes Research Center, Department of Radiation Medicine, School of Basic Medical Sciences, Peking University, Beijing, 100191, People's Republic of China.
Huiyun ZhaoMedical Isotopes Research Center, Department of Radiation Medicine, School of Basic Medical Sciences, Peking University, Beijing, 100191, People's Republic of China.
Yakun WanShanghai Novamab Biopharmaceuticals Co., Ltd, Shanghai, People's Republic of China.
Bing JiaMedical Isotopes Research Center, Department of Radiation Medicine, School of Basic Medical Sciences, Peking University, Beijing, 100191, People's Republic of China. jiabing@bjmu.edu.cn.
Fan WangMedical Isotopes Research Center, Department of Radiation Medicine, School of Basic Medical Sciences, Peking University, Beijing, 100191, People's Republic of China. wangfan@bjmu.edu.cn.
Peking University · CNChinese Academy of Sciences · CNInstitute of Biophysics · CN

Funding

Key Technologies Research and Development Program 2017YFA0205600National Natural Science Foundation of China 81621063National Natural Science Foundation of China 81630045National Natural Science Foundation of China 81871416National Natural Science Foundation of China 81927802
6 · The paper itself

Abstract

purposeOverexpression of epithelial cell adhesion molecule (EpCAM) plays essential roles in tumorigenesis and tumor progression in almost all epithelium-derived cancer. Monitoring EpCAM expression in tumors can be used for the diagnosis, staging, and prognosis of cancer patients, as well as guiding the individualized treatment of EpCAM-targeted drugs. In this study, we described the synthesis and evaluation of a site-specifically [

methodsWe first prepared the [

results[

conclusion[

Indexed as

NeoplasmsTomography, Emission-Computed, Single-PhotonAnimalsCell Line, TumorEpithelial Cell Adhesion MoleculeHumansSingle Photon Emission Computed Tomography Computed TomographyTechnetiumEPCAM protein, humanEpithelial Cell Adhesion MoleculeTechnetium[99mTc]Tc-NanobodyEpCAM imagingImmuno-SPECT/CTSite-specific radiolabeling

Identifiers

PMID35013776
OpenAlexW4226140681

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.