Evidence map›Paper›PMID 35013762›Full record

Trial reportPsychopharmacology2022

"Push it!" or "Hold it!"? A comparison of nicotine-avoidance training and nicotine-inhibition training in smokers motivated to quit.

Alla Machulska, Mike Rinck, Tim Klucken, Kristian Kleinke, Jana-Carina Wunder, Olga Remeniuk, Jürgen Margraf

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Psychopharmacology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Approach Bias and Tobacco Craving as Mechanisms of the Effect of Approach Bias Retraining on Smoking Cessation.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Alla MachulskaDepartment of Clinical Psychology, Institute of Psychology, University of Siegen, Adolf-Reichwein-Str. 2a, D-57068, Siegen, Germany. alla.machulska@uni-siegen.de.ORCID http://orcid.org/0000-0001-5968-429X
Mike RinckBehavioural Science Institute, Radboud University Nijmegen, Nijmegen, The Netherlands.
Tim KluckenDepartment of Clinical Psychology, Institute of Psychology, University of Siegen, Adolf-Reichwein-Str. 2a, D-57068, Siegen, Germany.
Kristian KleinkeDepartment of Clinical Psychology, Institute of Psychology, University of Siegen, Adolf-Reichwein-Str. 2a, D-57068, Siegen, Germany.
Jana-Carina WunderMental Health Research and Treatment Center, Ruhr-Universität Bochum, Bochum, Germany.
Olga RemeniukMental Health Research and Treatment Center, Ruhr-Universität Bochum, Bochum, Germany.
Jürgen MargrafMental Health Research and Treatment Center, Ruhr-Universität Bochum, Bochum, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

rationaleRecently, experimental paradigms have been developed to strengthen automatic avoidance or inhibitory responses for smoking cues. However, these procedures have not yet been directly compared regarding their effectiveness and mechanisms of action.

objectiveThis study compared the effects of avoidance vs. inhibitory training as an add-on to a brief smoking cessation intervention. The standard Approach-Avoidance-Task (AAT) was adapted for both training types and control conditions.

methodsOne hundred twenty-four smokers attended behavioral counseling for smoking cessation and were thereafter randomized to one of four training conditions: avoidance-AAT, sham-avoidance-AAT, inhibition-AAT, sham-inhibition-AAT. During a 2-week training period including five training sessions, smokers in the avoidance-AAT trained to implicitly avoid all smoking-related cues, while smokers in the inhibition-AAT trained to implicitly inhibit behavioral response to smoking cues. During sham training, no such contingencies appeared. Self-report and behavioral data were assessed before and after training. Cigarette smoking and nicotine dependence were also assessed at 4- and 12-week follow-ups.

resultsAt posttest, avoidance training was more effective in reducing daily smoking than inhibition training. However, this difference was no longer evident in follow-up assessments. All training conditions improved other smoking- and health-related outcomes. Neither training changed smoking-related approach biases or associations, but approach biases for smoking-unrelated pictures increased and Stroop interference decreased in all conditions. Smoking devaluation was also comparable in all groups.

conclusionsAvoidance training might be slightly more effective in reducing smoking than inhibitory training. Overall, however, all four training types yielded equivalent therapy and training effects. Hence, a clear preference for one type of training remains premature.

Indexed as

Smoking CessationTobacco Use DisorderHumansNicotineSmokersSmokingNicotineApproach-Avoidance-TaskApproach biasApproach bias modificationCigarette smokingInhibition trainingInhibitory trainingNicotine addictionSmoking cessation

Identifiers

PMID35013762
PMCPMC8748000

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.