Observational studyPediatric research2022
Early spectral EEG in preterm infants correlates with neurocognitive outcomes in late childhood.
Observational study in Pediatric research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 18 citations in OpenAlex.
- Neurodevelopmental forecasting in preterms: aEEG at 32 weeks vs. MRI at term in predicting 2-year outcomes.Journal of perinatology : official journal of the California Perinatal Association · 2026Article
- Individual variability in neural correlates of visual engagement in premature toddlers.Developmental cognitive neuroscience · 2026Article
- Neurochemical-hemodynamic-electrophysiological coupling in the neonatal brain: a multimodal MRS-fMRI-EEG investigation.Frontiers in neuroscience · 2026Article
- Gestational Duration and Postnatal Age-Related Changes in Aperiodic and Periodic Parameters in Neonatal and Toddler Electroencephalogram (EEG).Human brain mapping · 2025Article
- aEEG in the first 3 days after extremely preterm delivery relates to neurodevelopmental outcomes.Journal of perinatology : official journal of the California Perinatal Association · 2024Article
- Early EEG-burst sharpness and 2-year disability in extremely preterm infants.Pediatric research · 2024Article
- Neuropsychology and Electroencephalography in Rural Children at Neurodevelopmental Risk: A Scoping Review.Pediatric reports · 2023Article
- An Animal Model of Neonatal Intensive Care Unit Exposure to Light and Sound in the Preterm Infant.Integrative and comparative biology · 2023Article
- Preterm birth accelerates the maturation of spontaneous and resting activity in the visual cortex.bioRxiv : the preprint server for biology · 2023Article
- Preterm birth accelerates the maturation of spontaneous and resting activity in the visual cortex.Frontiers in integrative neuroscience · 2023Article
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundEvidence regarding the predictive value of early amplitude-integrated electroencephalography (aEEG)/EEG on neurodevelopmental outcomes at school age and beyond is lacking. We aimed to investigate whether there is an association between early postnatal EEG and neurocognitive outcomes in late childhood.
methodsThis study is an observational prospective cohort study of premature infants with a gestational age <28 weeks. The total absolute band powers (tABP) of the delta, theta, alpha, and beta bands were analyzed from EEG recordings during the first three days of life. At 10-12 years of age, neurocognitive outcomes were assessed using the Wechsler Intelligence Scale for Children 4th edition (WISC-IV), Vineland adaptive behavior scales 2nd edition, and Behavior Rating Inventory of Executive Function (BRIEF). The mean differences in tABP were assessed for individuals with normal versus unfavorable neurocognitive scores.
resultsTwenty-two infants were included. tABP values in all four frequency bands were significantly lower in infants with unfavorable results in the main composite scores (full intelligence quotient, adaptive behavior composite score, and global executive composite score) on all three tests (p < 0.05).
conclusionsEarly postnatal EEG has the potential to assist in predicting cognitive outcomes at 10-12 years of age in extremely premature infants <28 weeks' gestation. IMPACT: Evidence regarding the value of early postnatal EEG in long-term prognostication in preterm infants is limited. Our study suggests that early EEG spectral analysis correlates with neurocognitive outcomes in late childhood in extremely preterm infants. Early identification of infants at-risk of later impairment is important to initiate early and targeted follow-up and intervention.
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