Evidence map›Paper›PMID 35013550›Full record

ArticleCommunications biology2022

Structure of putative tumor suppressor ALDH1L1.

Yaroslav Tsybovsky, Valentin Sereda, Marcin Golczak, Natalia I Krupenko, Sergey A Krupenko

Open access · goldAbstract read
In one paragraph

Article in Communications biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.0field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Yaroslav TsybovskyCancer Research Technology Program, Leidos Biomedical Research Inc., Frederick National Laboratory for Cancer Research, 8560 Progress Drive, Frederick, MD, 21701, USA. Yaroslav.Tsybovsky@nih.gov.ORCID http://orcid.org/0000-0002-2159-5248
Valentin SeredaNutrition Research Institute, University of North Carolina at Chapel Hill, 500 Laureate Way, Kannapolis, NC, 28081, USA.
Marcin GolczakDepartment of Pharmacology, School of Medicine, Case Western Reserve University, 10900 Euclid Ave, Cleveland, OH, 44106, USA.
Natalia I KrupenkoNutrition Research Institute, University of North Carolina at Chapel Hill, 500 Laureate Way, Kannapolis, NC, 28081, USA.ORCID http://orcid.org/0000-0003-2977-1557
Sergey A KrupenkoNutrition Research Institute, University of North Carolina at Chapel Hill, 500 Laureate Way, Kannapolis, NC, 28081, USA. sergey_krupenko@unc.edu.ORCID http://orcid.org/0000-0002-6926-2776
University of North Carolina at Chapel Hill · USCase Western Reserve University · USLeidos (United States) · US

Funding

MECHANISM OF ACTIONS OF A MAJOR FOLATE ENZYMER01DK054388 · NIDDK · VANDERBILT UNIVERSITY · PI KRUPENKO, SERGEY A · 1998 to 2015
$4.7M
Regulation of vitamin A metabolism in the eyeR01EY023948 · NEI · CASE WESTERN RESERVE UNIVERSITY · PI GOLCZAK, MARCIN BERNARD · 2014 to 2023
$3.8M
CCR NIH HHS HHSN261200800001CNCI NIH HHS HHSN261200800001ENEI NIH HHS R01 EY023948NIDDK NIH HHS R01 DK054388
6 · The paper itself

Abstract

Putative tumor suppressor ALDH1L1, the product of natural fusion of three unrelated genes, regulates folate metabolism by catalyzing NADP

Indexed as

Genes, Tumor SuppressorAnimalsCatalytic DomainFormyltetrahydrofolate DehydrogenaseOxidoreductases Acting on CH-NH Group DonorsRatsTumor Suppressor ProteinsFormyltetrahydrofolate DehydrogenaseOxidoreductases Acting on CH-NH Group DonorsTumor Suppressor Proteins

Identifiers

PMID35013550
PMCPMC8748788
OpenAlexW4206660125

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.