ArticleScientific reports2022
Metabolic and lifestyle factors in relation to senile cataract: a Mendelian randomization study.
Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 4 syntheses or guidelines pooled it, 39 citations in OpenAlex.
- Alcohol Exposure and Disease Associations: A Mendelian Randomization and Meta-Analysis on Weekly Consumption and Problematic Drinking.Nutrients · 2024Pooled it
- Pooled it
- Association between obesity and age-related cataract: an updated systematic review and dose-response meta-analysis of prospective cohort studies.Frontiers in nutrition · 2023Pooled it
- Pooled it
- Global, regional, national differences and gender disparity in the burden of cataract: current trends and future projections.Eye (London, England) · 2026Article
- Article
- Causal effect of obesity on cataract and mediating roles of metabolites: a Mendelian randomization study.International journal of ophthalmology · 2026Article
- The effect of type 2 diabetes genetic predisposition on non-cardiovascular comorbidities.Nature communications · 2025Article
- Association of Unhealthy Lifestyles with Cataract Risk, and The Mediating Role of Metabolic Signature: Analysis of the UK Biobank Prospective Cohort.Aging and disease · 2025Article
- From gene expression to causal associations: investigating the role of ferroptosis in cataract development.BMC medical genomics · 2025Article
- Genetic Correlation and Mendelian Randomization Analyses Support Causal Relationships Between Instant Coffee and Age-Related Macular Degeneration.Food science & nutrition · 2025Article
- The potential role of adipokines and hepatokines in age-related ocular diseases.Metabolism open · 2025Review
- Socioeconomic factors and the risk of eye diseases in an elderly Danish population.Journal of epidemiology and community health · 2025Article
- The effect of type 2 diabetes genetic predisposition on non-cardiovascular comorbidities.medRxiv : the preprint server for health sciences · 2025Article
- Self-reported myopia and age-related cataract: a two-sample Mendelian randomization study.Scientific reports · 2025Article
- Global, regional, and national burden of cataract: A comprehensive analysis and projections from 1990 to 2021.PloS one · 2025Article
- Risk prediction model for cataract after vitrectomy surgery: a 2-year study on primary rhegmatogenous retinal detachment.International journal of ophthalmology · 2025Article
- Thyroid Function, Diabetes, and Common Age-Related Eye Diseases: A Mendelian Randomization Study.Thyroid : official journal of the American Thyroid Association · 2024Article
- Application of mendelian randomization in ocular diseases: a review.Human genomics · 2024Review
- Causal associations between circulating inflammatory cytokines and blinding eye diseases: a bidirectional Mendelian randomization analysis.Frontiers in aging neuroscience · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
We conducted a Mendelian randomization study to determine the associations of body mass index (BMI), type 2 diabetes (T2D), systolic blood pressure (SBP), coffee and alcohol consumption and smoking initiation with senile cataract. Independent single nucleotide polymorphisms associated with the metabolic and lifestyle factors at the p < 5 × 10
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.