ArticleScientific reports2022
Region-specific complexity of the intracranial EEG in the sleeping human brain.
Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 27 citations in OpenAlex.
- Topographic Reorganization of EEG Complexity During Visual Mental Imagery: Insights from Lempel-Ziv Complexity in High-Density EEG.Brain topography · 2026Article
- Smart Wearable EEG Devices: A Review of Lightweight, Multi-Sensor Systems for Sleep and Everyday Neurophysiology.Biosensors · 2026Review
- Cognitive Processing and EEG Complexity.Entropy (Basel, Switzerland) · 2026Review
- Clusters in Thalamic iEEG Spectral Features Reveal Sleep/Wake Differences Over Time.Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society · 2026Article
- Scale-Free Neurodynamics as Functional Fingerprint of Brain Regions.Bioengineering (Basel, Switzerland) · 2026Article
- A Multifractal-Guided Machine Learning Framework for Late Post-Traumatic Seizure Prediction Following Hemorrhagic Traumatic Brain Injury.Research square · 2026Article
- Rapid eye movement sleep displays distinct fractal dynamics between phasic and tonic states.Neuroscience of consciousness · 2026Article
- Article
- EEG difference in the Higuchi fractal dimension of wakefulness and sleep from birth to adolescence.PloS one · 2025Article
- An Electroencephalogram Signature of Melanin-Concentrating Hormone Neuron Activities Predicts Cocaine Seeking.Biological psychiatry · 2024Article
- Overlap of spike and ripple propagation onset predicts surgical outcome in epilepsy.Annals of clinical and translational neurology · 2024Article
- An EEG Signature of MCH Neuron Activities Predicts Cocaine Seeking.bioRxiv : the preprint server for biology · 2024Article
- Fractal Time Series: Background, Estimation Methods, and Performances.Advances in neurobiology · 2024Review
- Clinical Sensitivity of Fractal Neurodynamics.Advances in neurobiology · 2024Article
- Correlation between electroencephalographic markers in the healthy brain.Scientific reports · 2023Article
- Functional Source Separation-Identified Epileptic Network: Analysis Pipeline.Brain sciences · 2022Article
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
As the brain is a complex system with occurrence of self-similarity at different levels, a dedicated analysis of the complexity of brain signals is of interest to elucidate the functional role of various brain regions across the various stages of vigilance. We exploited intracranial electroencephalogram data from 38 cortical regions using the Higuchi fractal dimension (HFD) as measure to assess brain complexity, on a dataset of 1772 electrode locations. HFD values depended on sleep stage and topography. HFD increased with higher levels of vigilance, being highest during wakefulness in the frontal lobe. HFD did not change from wake to stage N2 in temporo-occipital regions. The transverse temporal gyrus was the only area in which the HFD did not differ between any two vigilance stages. Interestingly, HFD of wakefulness and stage R were different mainly in the precentral gyrus, possibly reflecting motor inhibition in stage R. The fusiform and parahippocampal gyri were the only areas showing no difference between wakefulness and N2. Stages R and N2 were similar only for the postcentral gyrus. Topographical analysis of brain complexity revealed that sleep stages are clearly differentiated in fronto-central brain regions, but that temporo-occipital regions sleep differently.
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