Evidence map›Paper›PMID 35013343›Full record

Trial reportNPJ primary care respiratory medicine2022

Effectiveness of individualized inhaler technique training on low adherence (LowAd) in ambulatory patients with COPD and asthma.

Juan Miguel Sánchez-Nieto, Roberto Bernabeu-Mora, Irene Fernández-Muñoz, Andrés Carrillo-Alcaraz, Juan Alcántara-Fructuoso, Javier Fernández-Alvarez, Juan Carlos Vera-Olmos, María José Martínez-Ferre, Mercedes Garci-Varela Olea, Maria José Córcoles Valenciano and 1 more

Open access · goldAbstract readClinical Trial
In one paragraph

Trial report in NPJ primary care respiratory medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 22 citations in OpenAlex.

  1. Review
  2. Recent Advances in Inhalation Therapy: An Overview.Pharmaceuticals (Basel, Switzerland) · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Treatment Adherence in Patients with Obstructive Pulmonary Diseases.International journal of environmental research and public health · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Juan Miguel Sánchez-NietoDivision of Pneumology, Morales Meseguer General University Hospital, 30008, Murcia, Spain.
Roberto Bernabeu-MoraDivision of Pneumology, Morales Meseguer General University Hospital, 30008, Murcia, Spain. rbernabeumora@hotmail.com.ORCID 0000-0002-7426-2316
Irene Fernández-MuñozDivision of Pneumology, Morales Meseguer General University Hospital, 30008, Murcia, Spain.
Andrés Carrillo-AlcarazDivision of Intensive Care Unit, Morales Meseguer General University Hospital, 30008, Murcia, Spain.ORCID 0000-0002-1937-6855
Juan Alcántara-FructuosoDivision of Pneumology, Morales Meseguer General University Hospital, 30008, Murcia, Spain.
Javier Fernández-AlvarezDivision of Pneumology, Morales Meseguer General University Hospital, 30008, Murcia, Spain.
Juan Carlos Vera-OlmosDivision of Pneumology, Morales Meseguer General University Hospital, 30008, Murcia, Spain.
María José Martínez-FerreDivision of Pneumology, Morales Meseguer General University Hospital, 30008, Murcia, Spain.
Mercedes Garci-Varela OleaDivision of Pneumology, Morales Meseguer General University Hospital, 30008, Murcia, Spain.
Maria José Córcoles ValencianoDivision of Pneumology, Morales Meseguer General University Hospital, 30008, Murcia, Spain.
Diego Salmerón MartínezInstitute for Bio-health Research of Murcia (IMIB-Arrixaca), El Palmar, 30120, Murcia, Spain.ORCID 0000-0002-4574-6880
Hospital General Universitario Morales Meseguer · ESInstituto Murciano de Investigación Biosanitaria · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To analyze whether there is improvement in adherence to inhaled treatment in patients with COPD and asthma after an educational intervention based on the teach-to-goal method. This is a prospective, non-randomized, single-group study, with intervention and before-after evaluation. The study population included 120 patients (67 females and 53 males) diagnosed with asthma (70.8%) and COPD (29.1%). The level of adherence (low and optimal) and the noncompliance behavior pattern (erratic, deliberate and unwitting) were determined by the Test of the adherence to Inhalers (TAI). This questionnaire allows you to determine the level of adherence and the types of noncompliance. Low Adherence (LowAd) was defined as a score less than 49 points. All patients received individualized educational inhaler technique intervention (IEITI). Before the IEITI, 67.5% of the patients had LowAd. Following IEITI, on week 24, LowAd was 55% (p = 0.024). Each patient can present one or more types of noncompliance. The most frequent type was forgetting to use the inhaler (erratic), 65.8%. The other types were deliberate: 43.3%, and unwitting: 57.5%. All of them had decreased on the final visit: 51.7% (p = 0.009), 25.8% (p = 0.002), 39.2% (p = 0.002). There were no significant differences in adherence between asthma and COPD patients at the start of the study. The only predicting factor of LowAd was the female gender. An individualized educational intervention, in ambulatory patients with COPD and asthma, in real-world clinical practice conditions, improves adherence to the inhaled treatment.

Indexed as

AsthmaPulmonary Disease, Chronic ObstructiveAdministration, InhalationFemaleHumansMaleMedication AdherenceNebulizers and VaporizersProspective Studies

Identifiers

PMID35013343
PMCPMC8748930
OpenAlexW4206368240

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.