Evidence map›Paper›PMID 35013000›Full record

ArticleThorax2022

Secondhand nicotine vaping at home and respiratory symptoms in young adults.

Talat Islam, Jessica Braymiller, Sandrah P Eckel, Feifei Liu, Alayna P Tackett, Meghan E Rebuli, Jessica Barrington-Trimis, Rob McConnell

Open access · hybridAbstract read
In one paragraph

Article in Thorax, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 1 pooled it
6.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 1 synthesis or guideline pooled it, 58 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Vaping-related lung disease: a narrative review.Journal of thoracic disease · 2026
    Review
  4. Review
  5. Review
  6. Article
  7. Review
  8. Assessing Nicotine Exposure in Users and Non-Users of Electronic Cigarettes Through Silicone Wristbands.International journal of environmental research and public health · 2025
    Article
  9. Article
  10. Article
  11. Article
  12. Characteristics of nicotine product use, perceptions of dependence, and passive exposure among first-year university students in Brazil.Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia · 2025
    Article
  13. Article
  14. Article
  15. Review
  16. Indoor air pollution and airway health.The Journal of allergy and clinical immunology · 2024
    Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Talat IslamDepartment of Population and Public Health Science, University of Southern California, Los Angeles, California, USA islam@usc.edu.ORCID 0000-0002-2837-865X
Jessica BraymillerDepartment of Population and Public Health Science, University of Southern California, Los Angeles, California, USA.
Sandrah P EckelDepartment of Population and Public Health Science, University of Southern California, Los Angeles, California, USA.
Feifei LiuDepartment of Population and Public Health Science, University of Southern California, Los Angeles, California, USA.
Alayna P TackettDepartment of Population and Public Health Science, University of Southern California, Los Angeles, California, USA.
Meghan E RebuliDepartment of Pediatrics, Center for Environmental Medicine, Asthma and Lung Biology, University of North Carolina School of Medicine, Chapel Hill, North Carolina, USA.
Jessica Barrington-TrimisDepartment of Population and Public Health Science, University of Southern California, Los Angeles, California, USA.
Rob McConnellDepartment of Population and Public Health Science, University of Southern California, Los Angeles, California, USA.
University of Southern California · USUniversity of North Carolina at Chapel Hill · US

Funding

USC/NORRIS COMPREHENSIVE CANCER CENTER (CORE) SUPPORTP30CA014089 · NCI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Fumito Ito · 1985 to 2026
$181.4M
Translational Research Support CoreP30ES007048 · NIEHS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI ROB S MCCONNELL · 1996 to 2026
$46.4M
USC Tobacco Center of Regulatory ScienceU54CA180905 · NCI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Jessica Louise Barrington-Trimis · 2018 to 2026
$39.0M
UNC-CH CENTER FOR ENVIRONMENTAL HEALTH &SUSCEPTIBILITYP30ES010126 · NIEHS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Hazel B Nichols · 2001 to 2026
$36.3M
Diacetyl in e-cigarette flavorings: Acute and subacute pulmonary effectsR21HD084812 · NICHD · UNIVERSITY OF SOUTHERN CALIFORNIA · PI MCCONNELL, ROB S · 2015 to 2016
$457k
NCI NIH HHS P30 CA014089NCI NIH HHS U54 CA180905NICHD NIH HHS R21 HD084812NIEHS NIH HHS P30 ES007048NIEHS NIH HHS P30 ES010126
6 · The paper itself

Abstract

rationaleDespite high prevalence of e-cigarette use (vaping), little is currently known regarding the health effects of secondhand nicotine vape exposure.

objectiveTo investigate whether exposure to secondhand nicotine vape exposure is associated with adverse respiratory health symptoms among young adults.

methodWe investigated the effect of secondhand nicotine vape exposure on annually reported wheeze, bronchitic symptoms and shortness of breath in the prospective Southern California Children Health Study cohort. Data were collected from study participants (n=2097) with repeated annual surveys from 2014 (average age: 17.3 years) to 2019 (average age: 21.9). We used mixed effect logistic regression to evaluate the association between secondhand nicotine vape and respiratory symptoms after controlling for relevant confounders.

resultsPrevalence of secondhand nicotine vape increased from 11.7% to 15.6% during the study period in this population. Prevalence of wheeze, bronchitic symptoms and shortness of breath ranged from 12.3% to 14.9%, 19.4% to 26.0% and 16.5% to 18.1%, respectively, during the study period. Associations of secondhand nicotine vape exposure with bronchitic symptoms (OR 1.40, 95% CI 1.06 to 1.84) and shortness of breath (OR 1.53, 95% CI 1.06 to 2.21) were observed after controlling for vaping, active and passive exposure to tobacco or cannabis, and demographic characteristics (age, gender, race/ethnicity and parental education). Stronger associations were observed when analysis was restricted to participants who were neither smokers nor vapers. There were no associations with wheezing after adjustment for confounders.

conclusionSecondhand nicotine vape exposure was associated with increased risk of bronchitic symptoms and shortness of breath among young adults.

Indexed as

Electronic Nicotine Delivery SystemsVapingAdolescentDyspneaHumansNicotineProspective StudiesRespiratory SoundsYoung AdultNicotinetobacco and the lung

Identifiers

PMID35013000
PMCPMC9203939
OpenAlexW4206793580

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.