Evidence map›Paper›PMID 35012987›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2022

Dengue virus infection modifies mosquito blood-feeding behavior to increase transmission to the host.

Benjamin Wong Wei Xiang, Wilfried A A Saron, James C Stewart, Arthur Hain, Varsha Walvekar, Dorothée Missé, Fréderic Thomas, R Manjunatha Kini, Benjamin Roche, Adam Claridge-Chang and 2 more

Open access · hybridAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
11.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it, 61 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. First record of Zika virus in Yemen.Current research in parasitology & vector-borne diseases · 2026
    Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Gaussian Process Emulation for Exploring Complex Infectious Disease Models.medRxiv : the preprint server for health sciences · 2025
    Article
  16. Article
  17. Review
  18. Review
  19. iScience · 2024
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 3 countries.

Benjamin Wong Wei XiangProgramme in Emerging Infectious Diseases, Duke-National University of Singapore (NUS) Medical School, Singapore 169857, Singapore.ORCID 0000-0002-1394-484X
Wilfried A A SaronProgramme in Emerging Infectious Diseases, Duke-National University of Singapore (NUS) Medical School, Singapore 169857, Singapore.ORCID 0000-0002-7974-5288
James C StewartProgramme in Neuroscience and Behavioral Disorder, Duke-NUS School, Singapore 169857, Singapore.
Arthur HainProgramme in Emerging Infectious Diseases, Duke-National University of Singapore (NUS) Medical School, Singapore 169857, Singapore.
Varsha WalvekarDepartment of Biological Sciences, National University of Singapore, Singapore 117558, Singapore.
Dorothée MisséMaladies Infectieuses et Vecteurs: Ecologie, Génétique, Evolution et Contrôle (MIVEGEC), Université Montpellier, Institut de Recherche pour le Développement (IRD), CNRS, 34394 Montpellier, France.
Fréderic ThomasCentre de Recherches Ecologiques et Evolutives sur le Cancer (CREEC), CNRS, Université Montpellier, 34394 Montpellier, France.
R Manjunatha KiniDepartment of Biological Sciences, National University of Singapore, Singapore 117558, Singapore.ORCID 0000-0002-6100-3251
Benjamin RocheMaladies Infectieuses et Vecteurs: Ecologie, Génétique, Evolution et Contrôle (MIVEGEC), Université Montpellier, Institut de Recherche pour le Développement (IRD), CNRS, 34394 Montpellier, France.
Adam Claridge-ChangProgramme in Neuroscience and Behavioral Disorder, Duke-NUS School, Singapore 169857, Singapore.ORCID 0000-0002-4583-3650
Ashley L St JohnProgramme in Emerging Infectious Diseases, Duke-National University of Singapore (NUS) Medical School, Singapore 169857, Singapore.ORCID 0000-0001-5098-1044
Julien PomponProgramme in Emerging Infectious Diseases, Duke-National University of Singapore (NUS) Medical School, Singapore 169857, Singapore; julien.pompon@ird.fr.
National University of Singapore · SGCentre National de la Recherche Scientifique · FRDuke-NUS Medical School · SGSingHealth · SG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mosquito blood-feeding behavior is a key determinant of the epidemiology of dengue viruses (DENV), the most-prevalent mosquito-borne viruses. However, despite its importance, how DENV infection influences mosquito blood-feeding and, consequently, transmission remains unclear. Here, we developed a high-resolution, video-based assay to observe the blood-feeding behavior of

Indexed as

AedesAnimalsBehavior, AnimalDengueDengue VirusFeeding BehaviorHost-Pathogen InteractionsMultivariate Analysisblood-feeding behaviordengue virusepidemiologymosquitotransmission

Identifiers

PMID35012987
PMCPMC8785958
OpenAlexW4205737630

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.