ArticleProceedings of the National Academy of Sciences of the United States of America2022
Conservation of magnetite biomineralization genes in all domains of life and implications for magnetic sensing.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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15 citing papers in PubMed, 35 citations in OpenAlex.
- Endogenous iron biomineralization in the mouse spleen of metabolic diseases.Fundamental research · 2026Article
- Biosynthesis and function of magnetic organelles in magnetotactic bacteria.Nature reviews. Microbiology · 2026Review
- Epigenetics in Captivity: Restoring Wild Phenotypes in Captive-Reared Salmonids.Evolutionary applications · 2026Article
- Magnetic vector tomography reveals giant magnetofossils are optimised for magnetointensity reception.Communications earth & environment · 2025Article
- Activation of Cryptochrome 4 from Atlantic Herring.Biology · 2024Article
- Magnetosomes as Potential Nanocarriers for Cancer Treatment.Current drug delivery · 2024Review
- The origins of light-independent magnetoreception in humans.Frontiers in human neuroscience · 2024Review
- Harmonizing Magnetic Mitohormetic Regenerative Strategies: Developmental Implications of a Calcium-Mitochondrial Axis Invoked by Magnetic Field Exposure.Bioengineering (Basel, Switzerland) · 2023Review
- Renaissance for magnetotactic bacteria in astrobiology.The ISME journal · 2023Review
- Sense of doubt: inaccurate and alternate locations of virtual magnetic displacements may give a distorted view of animal magnetoreception ability.Communications biology · 2023Article
- Reply to Monteil et al.: Universal presence of core magnetite biomineralization genes points to ancient symbiosis.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Magnetosome proteins belong to universal protein families involved in many cell processes.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Magnetotactic bacteria and magnetofossils: ecology, evolution and environmental implications.NPJ biofilms and microbiomes · 2022Review
- Prussian blue technique is prone to yield false negative results in magnetoreception research.Scientific reports · 2022Article
- Searching for unity in diversity of animal magnetoreception: From biology to quantum mechanics and back.Innovation (Cambridge (Mass.)) · 2022Review
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Authors and funding
6 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Animals use geomagnetic fields for navigational cues, yet the sensory mechanism underlying magnetic perception remains poorly understood. One idea is that geomagnetic fields are physically transduced by magnetite crystals contained inside specialized receptor cells, but evidence for intracellular, biogenic magnetite in eukaryotes is scant. Certain bacteria produce magnetite crystals inside intracellular compartments, representing the most ancient form of biomineralization known and having evolved prior to emergence of the crown group of eukaryotes, raising the question of whether magnetite biomineralization in eukaryotes and prokaryotes might share a common evolutionary history. Here, we discover that salmonid olfactory epithelium contains magnetite crystals arranged in compact clusters and determine that genes differentially expressed in magnetic olfactory cells, contrasted to nonmagnetic olfactory cells, share ancestry with an ancient prokaryote magnetite biomineralization system, consistent with exaptation for use in eukaryotic magnetoreception. We also show that 11 prokaryote biomineralization genes are universally present among a diverse set of eukaryote taxa and that nine of those genes are present within the Asgard clade of archaea Lokiarchaeota that affiliates with eukaryotes in phylogenomic analysis. Consistent with deep homology, we present an evolutionary genetics hypothesis for magnetite formation among eukaryotes to motivate convergent approaches for examining magnetite-based magnetoreception, molecular origins of matrix-associated biomineralization processes, and eukaryogenesis.
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