Evidence map›Paper›PMID 35012917›Full record

ArticleNan fang yi ke da xue xue bao = Journal of Southern Medical University2021

[Photothermal effect of nano-copper sulfide against tongue squamous cell carcinoma].

D Chen, Z Chen, Z Wang, Y Yang, Y Jiang, C Hu

Abstract read
In one paragraph

Article in Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Advances in Photothermal Therapy for Oral Cancer.International journal of molecular sciences · 2025
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

D ChenDepartment of Stomatology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.
Z ChenDepartment of Stomatology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.
Z WangDepartment of Stomatology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.
Y YangDepartment of Stomatology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.
Y JiangDepartment of Stomatology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.
C HuDepartment of Stomatology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate the anti-tumor effect of BSA@CuS-PEG nanocomposites on tongue squamous cell carcinoma.

methodsTransmission electron microscopy, dynamic light scattering, Zeta potential and ultraviolet absorption spectroscopy were used to characterize the synthesized BSA@CuS-PEG nanocomposite, whose photothermal properties was assessed with near infrared Ⅱ region excitation light (1064 nm). The cytotoxicity of the nanocomposite in Cal27 and SCC9 cells was evaluated using CCK-8 assay, and its effect on cell cycle distribution was analyzed using flow cytometry. The

resultsThe synthesized BSA@CuS-PEG nanocomposite showed a temperature variation (ΔT) of about 30 ℃ under near-infrared (NIR) irradiation (0.5 W/cm2), suggesting its excellent photothermal sensitivity. CCK-8 assay showed that BSA@CuS-PEG had no significant toxicity to tumor cells, but upon NIR irradiation, the nanocomposite produced a significant stronger inhibitory effect on Cal27 and SCC9 cells than free nanocomposites (

conclusionThe BSA@CuS-PEG nanocomposite shows prominent photothermal properties and good anti-tumor effects both

Indexed as

Carcinoma, Squamous CellNanoparticlesTongue NeoplasmsAnimalsCopperMicePhototherapySulfidesTongueCopperSulfidescopper sulfidenanocompositesphotothermal therapytongue cancer

Identifiers

PMID35012917
PMCPMC8752421

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.