Evidence map›Paper›PMID 35012904›Full record

ArticleTrends in cancer2022

Dissecting liver tumor heterogeneity to improve health equity.

Lichun Ma, Xin Wei Wang

Abstract read
In one paragraph

Article in Trends in cancer, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Lichun MaLaboratory of Human Carcinogenesis, Center for Cancer Research, National Cancer Institute, Bethesda, MD 20892, USA. Electronic address: lichun.ma@nih.gov.
Xin Wei WangLaboratory of Human Carcinogenesis, Center for Cancer Research, National Cancer Institute, Bethesda, MD 20892, USA; Liver Cancer Program, Center for Cancer Research, National Cancer Institute, Bethesda, MD 20892, USA. Electronic address: xw3u@nih.gov.

Funding

Strategies for improving early detection, diagnosis and treatment of liver cancerZIABC010313 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI WANG, XIN WEI · 2009 to 2025
$18.1M
The role of cancer stem cells in liver cancer heterogeneity and subtypesZIABC010876 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI WANG, XIN WEI · 2009 to 2025
$12.6M
Liver Cancer ProgramZIABC011870 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI WANG, XIN WEI · 2019 to 2025
$10.1M
The identification of human hepatocellular carcinoma metastasis genesZIABC010877 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI WANG, XIN WEI · 2009 to 2025
$8.3M
Identification of viral exposure signatures for early detection of liver cancerZICBC012048 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI WANG, LIMIN · 2021 to 2025
$2.2M
Tumor heterogeneity in liver cancerZIABC012079 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI MA, LICHUN · 2022 to 2025
$1.9M
Molecular signatures for liver cancer diagnosis and treatment stratificationZ01BC010313 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI WANG, XIN WEI · 1999 to 2008
$1.8M
The role of cancer stem cells in liver cancer heterogeneity and subtypesZ01BC010876 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI WANG, XIN · 2008 to 2008
$490k
The identification of human hepatocellular carcinoma metastasis genesZ01BC010877 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI WANG, XIN · 2008 to 2008
$327k
Intramural NIH HHS Z01 BC010313Intramural NIH HHS Z01 BC010876Intramural NIH HHS Z01 BC010877Intramural NIH HHS ZIA BC010313Intramural NIH HHS ZIA BC010876Intramural NIH HHS ZIA BC010877Intramural NIH HHS ZIA BC011870
6 · The paper itself

Abstract

Liver cancer burden varies greatly among populations. This disparity stems from the presence of complex etiology, sex, race/ethnicity, and extensive tumor molecular heterogeneity. Our ability to dissect tumor heterogeneity and to identify shared common features of liver cancer in diverse populations may improve precision medicine, thereby reducing disease burden.

Indexed as

Health EquityLiver NeoplasmsEthnicityHumansPrecision Medicinehealth disparityhealth equityhepatocellular carcinomaliver cancerprecision medicinetumor heterogeneity

Identifiers

PMID35012904
PMCPMC9058969

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.