Evidence map›Paper›PMID 35012829›Full record

ArticleAmerican journal of preventive medicine2022

Appropriateness of Antibiotic Prophylaxis Before Dental Procedures, 2016-2018.

Colin C Hubbard, Charlesnika T Evans, Gregory S Calip, Jifang Zhou, Susan A Rowan, Katie J Suda

Abstract read
In one paragraph

Article in American journal of preventive medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Colin C HubbardDivision of Hospital Medicine, Department of Medicine, University of California San Francisco, San Francisco, California.
Charlesnika T EvansCenter of Innovation for Complex Chronic Healthcare, Edward Hines, Jr. VA Hospital, Hines, Illinois; Department of Preventive Medicine, Center for Health Services and Outcomes Research, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.
Gregory S CalipCollege of Pharmacy, University of Illinois Chicago, Chicago, Illinois.
Jifang ZhouSchool of International Pharmaceutical Business, China Pharmaceutical University, Nanjing, China.
Susan A RowanCollege of Dentistry, University of Illinois Chicago, Chicago, Illinois.
Katie J SudaSchools of Medicine and Pharmacy, University of Pittsburgh, Pittsburgh, Pennsylvania; Center for Health Equity Research and Promotion, VA Pittsburgh Healthcare System, Pittsburgh, Pennsylvania. Electronic address: ksuda@pitt.edu.

Funding

Dental prescribing of antibiotics and opioids: high use in the absence of evidenceR01HS025177 · AHRQ · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI SUDA, KJ · 2017 to 2020
$1.4M
HSR&D Research Career Scientist AwardIK6HX003156 · VA · EDWARD HINES JR VA HOSPITAL · PI EVANS, CHARLESNIKA T · 2020 to 2025
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AHRQ HHS R01 HS025177HSRD VA IK6 HX003156
6 · The paper itself

Abstract

introductionPrescribing antibiotic prophylaxis is common yet unnecessary for many dental visits. In this analysis, our objective was to assess whether the appropriateness of antibiotic prophylaxis has improved over time.

methodsA retrospective cohort study was conducted using dental visits from 2016 to 2018 (data analyzed in 2021) using medical and prescriptions claims data of patients from the U.S. with commercial dental insurance. Antibiotic prophylaxis was defined as a ≤2 days' supply prescription dispensed within 7 days before a dental visit. Appropriateness of prophylaxis was defined on the basis of the manipulation of the gingiva/tooth periapex or oral mucosa perforation in patients with appropriate cardiac diagnoses. Associations between patient and visit characteristics and appropriateness of antibiotic prophylaxis were assessed using multiple Poisson regression.

resultsUnnecessary antibiotic prophylaxis was highly prevalent in this cohort, ranging from 77.0% in 2016 to 78.5% in 2018. In the adjusted analysis, factors associated with unnecessary antibiotic prophylaxis included younger age, female sex, geographic region, rurality, type of antibiotic, and certain dental procedures. The factors associated with the highest risk of unnecessary prophylaxis in the adjusted analysis were orthodontic procedures and having a history of a prosthetic joint. Notably, the risk of unnecessary antibiotic prophylaxis decreased over time in the adjusted analysis.

conclusionsUnnecessary prescription of antibiotic prophylaxis by dentists continues to be common. Antimicrobial stewardship strategies are needed to improve prescribing by dentists.

Indexed as

Anti-Bacterial AgentsAntibiotic ProphylaxisCohort StudiesDentistryFemaleHumansRetrospective StudiesAnti-Bacterial Agents

Identifiers

PMID35012829
PMCPMC9133147

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.