Evidence map›Paper›PMID 35012776›Full record

ArticleVaccine2022

Impact of the COVID-19 pandemic on pediatric and adolescent vaccinations and well child visits in the United States: A database analysis.

Stephanie A Kujawski, Lixia Yao, H Echo Wang, Cristina Carias, Ya-Ting Chen

Abstract read
In one paragraph

Article in Vaccine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

51 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Material economic hardships are associated with second-year hospitalizations after pediatric liver transplantation: Results from the SOCIAL-Tx study.Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society · 2026
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  8. Prenatal Care Coordination and Well-Child Visit Receipt in Early Childhood.Journal of the American Board of Family Medicine : JABFM · 2025
    Article
  9. Article
  10. Article
  11. Evaluating the Impact of the COVID-19 Pandemic on Pediatric Asthma Incidence.The journal of allergy and clinical immunology. In practice · 2025
    Review
  12. Article
  13. Article
  14. Article
  15. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Stephanie A KujawskiMerck & Co., Inc, 2000 Galloping Hill Road, Kenilworth, NJ 07033, USA. Electronic address: stephanie.kujawski@merck.com.
Lixia YaoMerck & Co., Inc, 2000 Galloping Hill Road, Kenilworth, NJ 07033, USA. Electronic address: lixia.yao@merck.com.
H Echo WangMerck & Co., Inc, 2000 Galloping Hill Road, Kenilworth, NJ 07033, USA. Electronic address: haoying.wang@merck.com.
Cristina CariasMerck & Co., Inc, 2000 Galloping Hill Road, Kenilworth, NJ 07033, USA. Electronic address: cristina.da.silva.carias@merck.com.
Ya-Ting ChenMerck & Co., Inc, 2000 Galloping Hill Road, Kenilworth, NJ 07033, USA. Electronic address: yating_chen@merck.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe COVID-19 pandemic has disrupted healthcare, including immunization practice and well child visit attendance. Maintaining vaccination coverage is important to prevent disease outbreaks and morbidity. We assessed the impact of the COVID-19 pandemic on pediatric and adolescent vaccination administration and well child visit attendance in the United States.

methodsThis cross-sectional study used IBM MarketScan Commercial Database (IMC) with Early View (healthcare claims database) and TriNetX Dataworks Global Network (electronic medical records database) from January 2018-March 2021. Individuals ≤ 18 years of age who were enrolled during the analysis month of interest (IMC with Early View) or had ≥ 1 health encounter at a participating institution (TriNetX Dataworks) were included. We calculated the monthly percent difference between well child visit attendance and vaccine administration rates for 10 recommended pediatric/adolescent vaccines in 2020 and 2021 compared with 2018-2019. Data were stratified by the age groups 0-2 years, 4-6 years, and 9-16 years.

resultsIn IMC with Early View, the average monthly enrollment for children 0-18 years of age was 5.2 million. In TriNetX Dataworks, 12.2 million eligible individuals were included. Well child visits and vaccinations reached the lowest point in April 2020 compared with 2018-2019. Well child visit attendance and vaccine administration rates were inversely related to age, with initial reductions highest for adolescents and lowest for ages 0-2 years. Rates rebounded in June and September 2020 and stabilized to pre-pandemic levels in Fall 2020. Rates dropped below baseline in early 2021 for groups 0-2 years and 4-6 years.

conclusionsWe found substantial disruptions in well child visit attendance and vaccination administration for children and adolescents during the COVID-19 pandemic in 2020 and early 2021. Continued efforts are needed to monitor recovery and catch up to avoid outbreaks and morbidity associated with vaccine-preventable diseases.

Indexed as

COVID-19PandemicsAdolescentChildChild, PreschoolCross-Sectional StudiesHumansInfantInfant, NewbornSARS-CoV-2United StatesVaccinationAdolescentsCOVID-19Infectious diseasePediatricsVaccination coverageWell-child visits

Identifiers

PMID35012776
PMCPMC8719942

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.